Identity
HGNC
LOCATION
1q25.3
LOCUSID
ALIAS
GLNS,GS,PIG43,PIG59
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2752
MIM: 138290
HGNC: 4341
Ensembl: ENSG00000135821
Variants:
dbSNP: 2752
ClinVar: 2752
TCGA: ENSG00000135821
COSMIC: GLUL
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38086219 | 2024 | Leat-associated seizures the possible role of EAAT2, pyruvate carboxylase and glutamine synthetase. | 0 |
| 38579670 | 2024 | Clustered de novo start-loss variants in GLUL result in a developmental and epileptic encephalopathy via stabilization of glutamine synthetase. | 0 |
| 38086219 | 2024 | Leat-associated seizures the possible role of EAAT2, pyruvate carboxylase and glutamine synthetase. | 0 |
| 38579670 | 2024 | Clustered de novo start-loss variants in GLUL result in a developmental and epileptic encephalopathy via stabilization of glutamine synthetase. | 0 |
| 36587392 | 2023 | Single-cell and spatial analyses reveal the association between gene expression of glutamine synthetase with the immunosuppressive phenotype of APOE+CTSZ+TAM in cancers. | 3 |
| 36619229 | 2023 | Glutamine synthetase regulates the immune microenvironment and cancer development through the inflammatory pathway. | 2 |
| 36702251 | 2023 | Multiple oxidative post-translational modifications of human glutamine synthetase mediate peroxynitrite-dependent enzyme inactivation and aggregation. | 1 |
| 37531433 | 2023 | PHF8-GLUL axis in lipid deposition and tumor growth of clear cell renal cell carcinoma. | 3 |
| 37979911 | 2023 | Glutamine synthetase and hepatocellular carcinoma. | 0 |
| 36587392 | 2023 | Single-cell and spatial analyses reveal the association between gene expression of glutamine synthetase with the immunosuppressive phenotype of APOE+CTSZ+TAM in cancers. | 3 |
| 36619229 | 2023 | Glutamine synthetase regulates the immune microenvironment and cancer development through the inflammatory pathway. | 2 |
| 36702251 | 2023 | Multiple oxidative post-translational modifications of human glutamine synthetase mediate peroxynitrite-dependent enzyme inactivation and aggregation. | 1 |
| 37531433 | 2023 | PHF8-GLUL axis in lipid deposition and tumor growth of clear cell renal cell carcinoma. | 3 |
| 37979911 | 2023 | Glutamine synthetase and hepatocellular carcinoma. | 0 |
| 36256480 | 2022 | Glutamine synthetase limits β-catenin-mutated liver cancer growth by maintaining nitrogen homeostasis and suppressing mTORC1. | 11 |
Citation
Dessen P
GLUL (glutamate-ammonia ligase)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45958/glul
