Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1268
MIM: 114610
HGNC: 2159
Ensembl: ENSG00000118432
Variants:
dbSNP: 1268
ClinVar: 1268
TCGA: ENSG00000118432
COSMIC: CNR1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10026 | aripiprazole | Chemical | ClinicalAnnotation | associated | PD | 20107430, 20631561, 23799528 | |
| PA128406954 | Weight gain | Disease | MultilinkAnnotation | associated | 24279860 | ||
| PA153906318 | Autism Spectrum Disorder | Disease | ClinicalAnnotation | associated | PD | 20107430, 20631561, 23799528 | |
| PA446878 | Cocaine-Related Disorders | Disease | ClinicalAnnotation | associated | |||
| PA447215 | Psychotic Disorders | Disease | ClinicalAnnotation | associated | PD | 20107430, 20631561, 23799528 | |
| PA447216 | Schizophrenia | Disease | ClinicalAnnotation | associated | PD | 20107430, 20631561, 23799528 | |
| PA449061 | clozapine | Chemical | ClinicalAnnotation | associated | PD | 20107430, 20631561, 23799528 | |
| PA449072 | cocaine | Chemical | ClinicalAnnotation | associated | |||
| PA449841 | haloperidol | Chemical | ClinicalAnnotation | associated | PD | 20107430, 20631561, 23799528 | |
| PA450688 | olanzapine | Chemical | ClinicalAnnotation | associated | PD | 20107430, 20631561, 23799528 | |
| PA451201 | quetiapine | Chemical | ClinicalAnnotation | associated | PD | 20107430, 20631561, 23799528 | |
| PA451257 | risperidone | Chemical | ClinicalAnnotation | associated | PD | 20107430, 20631561, 23799528 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35993329 | 2024 | Roles of cannabinoid CB1 and CB2 receptors in the modulation of psychostimulant responses. | 1 |
| 38159053 | 2024 | Deciphering the Molecular Association of Human CRIP1a with an Agonist-Bound Cannabinoid Receptor 1. | 0 |
| 38339011 | 2024 | Joint CB1 and NGF Receptor Activation Suppresses TRPM8 Activation in Etoposide-Resistant Retinoblastoma Cells. | 1 |
| 35993329 | 2024 | Roles of cannabinoid CB1 and CB2 receptors in the modulation of psychostimulant responses. | 1 |
| 38159053 | 2024 | Deciphering the Molecular Association of Human CRIP1a with an Agonist-Bound Cannabinoid Receptor 1. | 0 |
| 38339011 | 2024 | Joint CB1 and NGF Receptor Activation Suppresses TRPM8 Activation in Etoposide-Resistant Retinoblastoma Cells. | 1 |
| 35792570 | 2023 | The NPXXY Motif Regulates β-Arrestin Recruitment by the CB1 Cannabinoid Receptor. | 2 |
| 36250246 | 2023 | Cannabinoid 1 (CB(1) ) receptor arrestin subtype-selectivity and phosphorylation dependence. | 4 |
| 36440544 | 2023 | Association of CNR1 gene and cannabinoid 1 receptor protein in the human brain. | 4 |
| 36674826 | 2023 | M3 Receptor Pathway Stimulates Rapid Transcription of the CB1 Receptor Activation through Calcium Signalling and the CNR1 Gene Promoter. | 1 |
| 36716771 | 2023 | Regional redistribution of CB1 cannabinoid receptors in human foetal brains with Down's syndrome and their functional modifications in Ts65Dn(+/+) mice. | 1 |
| 36869624 | 2023 | Cannabinoid regulation of neurons in the dentate gyrus during epileptogenesis: Role of CB1R-associated proteins and downstream pathways. | 0 |
| 36918037 | 2023 | Lifetime cannabis use and childhood trauma associated with CNR1 genetic variants increase the risk of psychosis: findings from the STREAM study. | 0 |
| 36972648 | 2023 | The association of CNR1 genetic variants with resting-state functional connectivity in youth bipolar disorder. | 0 |
| 37611908 | 2023 | Cannabinoid receptor gene CNR1 is downregulated in subcortical brain samples and upregulated in blood samples of individuals with schizophrenia: A participant data systematic meta-analysis. | 3 |
Citation
Dessen P
CNR1 (cannabinoid receptor 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45964/cnr1
