IL13RA2 (interleukin 13 receptor subunit alpha 2)

2007-02-01  

Identity

HGNC
LOCATION
Xq23
LOCUSID
ALIAS
CD213A2,CT19,IL-13R,IL13BP

Other Information

Locus ID:

NCBI: 3598
MIM: 300130
HGNC: 5975
Ensembl: ENSG00000123496

Variants:

dbSNP: 3598
ClinVar: 3598
TCGA: ENSG00000123496
COSMIC: IL13RA2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000123496ENST00000243213Q14627
ENSG00000123496ENST00000371936Q14627

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Jak-STAT signaling pathwayKEGGko04630
Jak-STAT signaling pathwayKEGGhsa04630
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Signaling by InterleukinsREACTOMER-HSA-449147
Interleukin-4 and 13 signalingREACTOMER-HSA-6785807

References

Pubmed IDYearTitleCitations
367578022023IL-13RA2 downregulation in fibroblasts promotes keloid fibrosis via JAK/STAT6 activation.7
368067272023Identification of the α2 chain of interleukin-13 receptor as a potential biomarker for predicting castration resistance of prostate cancer using patient-derived xenograft models.1
367578022023IL-13RA2 downregulation in fibroblasts promotes keloid fibrosis via JAK/STAT6 activation.7
368067272023Identification of the α2 chain of interleukin-13 receptor as a potential biomarker for predicting castration resistance of prostate cancer using patient-derived xenograft models.1
335919972021IL-13Rα2 gene expression is a biomarker of adverse outcome in patients with adrenocortical carcinoma.2
336382962021Identification of serum interleukin-13 and interleukin-13 receptor subunit expressions: Rheumatoid arthritis-associated interstitial lung disease.8
338042632021Involvement of IL-4, IL-13 and Their Receptors in Pancreatic Cancer.29
340806462021IL13Rα2‑ and EGFR‑targeted pseudomonas exotoxin potentiates the TRAIL‑mediated death of GBM cells.3
341686432021M2a Macrophage-Secreted CHI3L1 Promotes Extracellular Matrix Metabolic Imbalances via Activation of IL-13Rα2/MAPK Pathway in Rat Intervertebral Disc Degeneration.25
345447972021IL13Rα2 Promotes Proliferation and Outgrowth of Breast Cancer Brain Metastases.8
335919972021IL-13Rα2 gene expression is a biomarker of adverse outcome in patients with adrenocortical carcinoma.2
336382962021Identification of serum interleukin-13 and interleukin-13 receptor subunit expressions: Rheumatoid arthritis-associated interstitial lung disease.8
338042632021Involvement of IL-4, IL-13 and Their Receptors in Pancreatic Cancer.29
340806462021IL13Rα2‑ and EGFR‑targeted pseudomonas exotoxin potentiates the TRAIL‑mediated death of GBM cells.3
341686432021M2a Macrophage-Secreted CHI3L1 Promotes Extracellular Matrix Metabolic Imbalances via Activation of IL-13Rα2/MAPK Pathway in Rat Intervertebral Disc Degeneration.25

Citation

Dessen P

IL13RA2 (interleukin 13 receptor subunit alpha 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45978/il13ra2