Identity
HGNC
LOCATION
9p13.3
LOCUSID
ALIAS
MTG,PRSS4,T9,TRY3,TRY4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5646
MIM: 613578
HGNC: 9486
Ensembl: ENSG00000010438
Variants:
dbSNP: 5646
ClinVar: 5646
TCGA: ENSG00000010438
COSMIC: PRSS3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37395651 | 2023 | Shear Stress Drives the Cleavage Activation of Protease-Activated Receptor 2 by PRSS3/Mesotrypsin to Promote Invasion and Metastasis of Circulating Lung Cancer Cells. | 1 |
| 37395651 | 2023 | Shear Stress Drives the Cleavage Activation of Protease-Activated Receptor 2 by PRSS3/Mesotrypsin to Promote Invasion and Metastasis of Circulating Lung Cancer Cells. | 1 |
| 35896602 | 2022 | Host neuronal PRSS3 interacts with enterovirus A71 3A protein and its role in viral replication. | 5 |
| 36618965 | 2022 | Serine Protease 3 Promotes Progression of Diffuse Large B-Cell Lymphoma and Serves as a Novel Prognostic Predictor. | 1 |
| 35896602 | 2022 | Host neuronal PRSS3 interacts with enterovirus A71 3A protein and its role in viral replication. | 5 |
| 36618965 | 2022 | Serine Protease 3 Promotes Progression of Diffuse Large B-Cell Lymphoma and Serves as a Novel Prognostic Predictor. | 1 |
| 33515547 | 2021 | Defective binding of SPINK1 variants is an uncommon mechanism for impaired trypsin inhibition in chronic pancreatitis. | 13 |
| 33758142 | 2021 | High Expression of PRSS3 Indicates Unfavorable Clinical Outcomes in Colon Adenocarcinoma. | 4 |
| 34195683 | 2021 | In-depth proteomics analysis of sentinel lymph nodes from individuals with endometrial cancer. | 17 |
| 33515547 | 2021 | Defective binding of SPINK1 variants is an uncommon mechanism for impaired trypsin inhibition in chronic pancreatitis. | 13 |
| 33758142 | 2021 | High Expression of PRSS3 Indicates Unfavorable Clinical Outcomes in Colon Adenocarcinoma. | 4 |
| 34195683 | 2021 | In-depth proteomics analysis of sentinel lymph nodes from individuals with endometrial cancer. | 17 |
| 31911942 | 2020 | PRSS contributes to cetuximab resistance in colorectal cancer. | 17 |
| 32014997 | 2020 | Inactivation of mesotrypsin by chymotrypsin C prevents trypsin inhibitor degradation. | 7 |
| 31911942 | 2020 | PRSS contributes to cetuximab resistance in colorectal cancer. | 17 |
Citation
Dessen P
PRSS3 (serine protease 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45981/prss3
