Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 85409
MIM: 607852
HGNC: 17046
Ensembl: ENSG00000145506
Variants:
dbSNP: 85409
ClinVar: 85409
TCGA: ENSG00000145506
COSMIC: NKD2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000145506 | ENST00000274150 | Q969F2 |
| ENSG00000145506 | ENST00000296849 | Q969F2 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Wnt signaling pathway | KEGG | ko04310 |
| Wnt signaling pathway | KEGG | hsa04310 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36820951 | 2023 | NKD2 Trigger NF-κB Signaling Pathway and Facilitates Thyroid Cancer Cell Proliferation. | 1 |
| 36820951 | 2023 | NKD2 Trigger NF-κB Signaling Pathway and Facilitates Thyroid Cancer Cell Proliferation. | 1 |
| 33045317 | 2021 | LINC00922 regulates epithelial-mesenchymal transition, invasive and migratory capacities in breast cancer through promoting NKD2 methylation. | 18 |
| 34433025 | 2021 | NKD2 mediates stimulation-dependent ORAI1 trafficking to augment Ca(2+) entry in T cells. | 2 |
| 33045317 | 2021 | LINC00922 regulates epithelial-mesenchymal transition, invasive and migratory capacities in breast cancer through promoting NKD2 methylation. | 18 |
| 34433025 | 2021 | NKD2 mediates stimulation-dependent ORAI1 trafficking to augment Ca(2+) entry in T cells. | 2 |
| 30941853 | 2019 | Protein kinase A-mediated phosphorylation of naked cuticle homolog 2 stimulates cell-surface delivery of transforming growth factor-α for epidermal growth factor receptor transactivation. | 5 |
| 30941853 | 2019 | Protein kinase A-mediated phosphorylation of naked cuticle homolog 2 stimulates cell-surface delivery of transforming growth factor-α for epidermal growth factor receptor transactivation. | 5 |
| 29126834 | 2018 | Low expression of NKD2 is associated with enhanced cell proliferation and poor prognosis in human hepatocellular carcinoma. | 4 |
| 29678899 | 2018 | ZFAS1 functions as an oncogenic long non-coding RNA in bladder cancer. | 17 |
| 29126834 | 2018 | Low expression of NKD2 is associated with enhanced cell proliferation and poor prognosis in human hepatocellular carcinoma. | 4 |
| 29678899 | 2018 | ZFAS1 functions as an oncogenic long non-coding RNA in bladder cancer. | 17 |
| 27246976 | 2017 | Long noncoding RNA ZFAS1 promotes gastric cancer cells proliferation by epigenetically repressing KLF2 and NKD2 expression. | 82 |
| 27246976 | 2017 | Long noncoding RNA ZFAS1 promotes gastric cancer cells proliferation by epigenetically repressing KLF2 and NKD2 expression. | 82 |
| 26902120 | 2016 | miR-130b targets NKD2 and regulates the Wnt signaling to promote proliferation and inhibit apoptosis in osteosarcoma cells. | 16 |
Citation
Dessen P
NKD2 (NKD inhibitor of WNT signaling pathway 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45982/nkd2
