Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4023
MIM: 609708
HGNC: 6677
Ensembl: ENSG00000175445
Variants:
dbSNP: 4023
ClinVar: 4023
TCGA: ENSG00000175445
COSMIC: LPL
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA446120 | Hypertriglyceridemia | Disease | ClinicalAnnotation | associated | PD | 19207029 | |
| PA449594 | fenofibrate | Chemical | ClinicalAnnotation | associated | PD | 19207029 | |
| PA451089 | pravastatin | Chemical | ClinicalAnnotation | associated | PD | 16103896 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38429792 | 2024 | Metabolic syndrome risk in adult coffee drinkers with the rs301 variant of the LPL gene. | 0 |
| 38530959 | 2024 | Association of lipoprotein lipase (LPL) gene variants with hyperlipidemic acute pancreatitis in southeastern Chinese population. | 0 |
| 38429792 | 2024 | Metabolic syndrome risk in adult coffee drinkers with the rs301 variant of the LPL gene. | 0 |
| 38530959 | 2024 | Association of lipoprotein lipase (LPL) gene variants with hyperlipidemic acute pancreatitis in southeastern Chinese population. | 0 |
| 36519608 | 2023 | The effect of AGTR1, AGТ, LPL, ADRB2 gene polymorphisms on central obesity in adolescents of the Kazakh population. | 1 |
| 36519761 | 2023 | Parkin regulates neuronal lipid homeostasis through SREBP2-lipoprotein lipase pathway-implications for Parkinson's disease. | 3 |
| 36652113 | 2023 | The breast cancer microenvironment and lipoprotein lipase: Another negative notch for a beneficial enzyme? | 1 |
| 36708756 | 2023 | Plasma Lipoprotein Lipase Is Associated with Risk of Future Major Adverse Cardiovascular Events in Patients Following Carotid Endarterectomy. | 0 |
| 36763533 | 2023 | Angiopoietin-like protein 4/8 complex-mediated plasmin generation leads to cleavage of the complex and restoration of LPL activity. | 8 |
| 37128695 | 2023 | Interaction between APOE, APOA1, and LPL Gene Polymorphisms and Variability in Changes in Lipid and Blood Pressure following Orange Juice Intake: A Pilot Study. | 0 |
| 37155355 | 2023 | Inverse association between apolipoprotein C-II and cardiovascular mortality: role of lipoprotein lipase activity modulation. | 0 |
| 37427758 | 2023 | Variants within the LPL gene confer susceptility to diabetic kidney disease and rapid decline in kidney function in Chinese patients with type 2 diabetes. | 1 |
| 37432202 | 2023 | Effect of the Interaction between Seaweed Intake and LPL Polymorphisms on Metabolic Syndrome in Middle-Aged Korean Adults. | 1 |
| 37550668 | 2023 | The East Asian-specific LPL p.Ala288Thr (c.862G > A) missense variant exerts a mild effect on protein function. | 2 |
| 37568214 | 2023 | Frameshift coding sequence variants in the LPL gene: identification of two novel events and exploration of the genotype-phenotype relationship for variants reported to date. | 2 |
Citation
Dessen P
LPL (lipoprotein lipase)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46016/lpl
