Identity
HGNC
LOCATION
18q12.1
LOCUSID
ALIAS
ATTR,CTS,CTS1,HEL111,HsT2651,PALB,TBPA,TTN
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7276
MIM: 176300
HGNC: 12405
Ensembl: ENSG00000118271
Variants:
dbSNP: 7276
ClinVar: 7276
TCGA: ENSG00000118271
COSMIC: TTR
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA166182756 | inotersen | Chemical | LabelAnnotation | associated | |||
| PA166184562 | tafamidis | Chemical | LabelAnnotation | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38008337 | 2024 | Characterization of the G-quadruplexes in the transthyretin gene and its role in silencing transthyretin mRNA transcription. | 0 |
| 38184135 | 2024 | Prevalence of transthyretin amyloid cardiomyopathy in patients admitted for acute heart failure. | 0 |
| 38289614 | 2024 | Transthyretin-Regulated Diabetic Retinopathy Through the VEGFA/PI3K/AKT Pathway. | 0 |
| 38399526 | 2024 | Rare c.302C>T TTR Variant Associated with Transthyretin Amyloidosis. | 0 |
| 38486098 | 2024 | Altered gut microbiota in Taiwanese A97S predominant transthyretin amyloidosis with polyneuropathy. | 0 |
| 38626647 | 2024 | Targeting TNF-α-induced expression of TTR and RAGE in rheumatoid arthritis: Apigenin's mediated therapeutic approach. | 0 |
| 38775614 | 2024 | Scintigraphic and Echocardiographic Study of Patients with Pathogenic or Probably Pathogenic Variants of the TTR Gene without Overt Cardiac Involvement. | 1 |
| 38843135 | 2024 | Modeling transthyretin (TTR) amyloid diseases, from monomer to amyloid fibrils. | 0 |
| 38008337 | 2024 | Characterization of the G-quadruplexes in the transthyretin gene and its role in silencing transthyretin mRNA transcription. | 0 |
| 38184135 | 2024 | Prevalence of transthyretin amyloid cardiomyopathy in patients admitted for acute heart failure. | 0 |
| 38289614 | 2024 | Transthyretin-Regulated Diabetic Retinopathy Through the VEGFA/PI3K/AKT Pathway. | 0 |
| 38399526 | 2024 | Rare c.302C>T TTR Variant Associated with Transthyretin Amyloidosis. | 0 |
| 38486098 | 2024 | Altered gut microbiota in Taiwanese A97S predominant transthyretin amyloidosis with polyneuropathy. | 0 |
| 38626647 | 2024 | Targeting TNF-α-induced expression of TTR and RAGE in rheumatoid arthritis: Apigenin's mediated therapeutic approach. | 0 |
| 38775614 | 2024 | Scintigraphic and Echocardiographic Study of Patients with Pathogenic or Probably Pathogenic Variants of the TTR Gene without Overt Cardiac Involvement. | 1 |
Citation
Dessen P
TTR (transthyretin)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46017/ttr
