PLXNB2 (plexin B2)

2006-10-01  

Identity

HGNC
PLXNB2
LOCATION
22q13.33
LOCUSID
23654
ALIAS
MM1,Nbla00445,PLEXB2,dJ402G11.3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23654
MIM: 604293
HGNC: 9104
Ensembl: ENSG00000196576

Variants:

dbSNP: 23654
ClinVar: 23654
TCGA: ENSG00000196576
COSMIC: PLXNB2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196576ENST00000359337O15031
ENSG00000196576ENST00000411680A6QRG9
ENSG00000196576ENST00000425954A6QRH1
ENSG00000196576ENST00000427829H0Y6J7
ENSG00000196576ENST00000432455E2PU09
ENSG00000196576ENST00000434732H0Y7X5
ENSG00000196576ENST00000449103O15031
ENSG00000196576ENST00000610984A0A087X000
ENSG00000196576ENST00000614805A0A087WU36

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Axon guidanceKEGGko04360
Axon guidanceKEGGhsa04360

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382957152024Colorectal Cancer-Associated Myofibroblasts Exhibit Enhanced Angiogenin Expression and Signaling via the PLXNB2 Receptor.0
384587522024Biallelic variants in Plexin B2 (PLXNB2) cause amelogenesis imperfecta, hearing loss and intellectual disability.0
382957152024Colorectal Cancer-Associated Myofibroblasts Exhibit Enhanced Angiogenin Expression and Signaling via the PLXNB2 Receptor.0
384587522024Biallelic variants in Plexin B2 (PLXNB2) cause amelogenesis imperfecta, hearing loss and intellectual disability.0
372725812023CircPLXNB2 regulates acute myeloid leukemia progression through miR-654-3p/CCND1 axis.1
376326332023Expression analysis, clinical significance and potential function of PLXNB2 in acute myeloid leukaemia.0
372725812023CircPLXNB2 regulates acute myeloid leukemia progression through miR-654-3p/CCND1 axis.1
376326332023Expression analysis, clinical significance and potential function of PLXNB2 in acute myeloid leukaemia.0
354182122022Angiogenin and plexin-B2 axis promotes glioblastoma progression by enhancing invasion, vascular association, proliferation and survival.7
354182122022Angiogenin and plexin-B2 axis promotes glioblastoma progression by enhancing invasion, vascular association, proliferation and survival.7
335148352021Plexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics.9
344146662021Increased airway epithelial cell-derived exosomes activate macrophage-mediated allergic inflammation via CD100 shedding.9
346500522021Plexin-B2 orchestrates collective stem cell dynamics via actomyosin contractility, cytoskeletal tension and adhesion.11
335148352021Plexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics.9
344146662021Increased airway epithelial cell-derived exosomes activate macrophage-mediated allergic inflammation via CD100 shedding.9

Citation

Dessen P

PLXNB2 (plexin B2)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/46040