ZDHHC17 (zinc finger DHHC-type palmitoyltransferase 17)

2007-02-01  

Identity

HGNC
LOCATION
12q21.2
LOCUSID
ALIAS
DHHC-17,DHHC17,HIP14,HIP3,HSPC294,HYPH
FUSION GENES

Other Information

Locus ID:

NCBI: 23390
MIM: 607799
HGNC: 18412
Ensembl: ENSG00000186908

Variants:

dbSNP: 23390
ClinVar: 23390
TCGA: ENSG00000186908
COSMIC: ZDHHC17

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000186908ENST00000426126Q8IUH5
ENSG00000186908ENST00000546778F8VUG7
ENSG00000186908ENST00000547604H0YIN1
ENSG00000186908ENST00000547620H0YHF0
ENSG00000186908ENST00000549682F8VPW2
ENSG00000186908ENST00000549944H0YI74
ENSG00000186908ENST00000550163H0YIP7
ENSG00000186908ENST00000550876F8VX48
ENSG00000186908ENST00000551407H0YHW0
ENSG00000186908ENST00000552453H0YIK0

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
319380472020Activation of JNK and p38 MAPK Mediated by ZDHHC17 Drives Glioblastoma Multiforme Development and Malignant Progression.32
319380472020Activation of JNK and p38 MAPK Mediated by ZDHHC17 Drives Glioblastoma Multiforme Development and Malignant Progression.32
287571452017Structural Basis for Substrate Recognition by the Ankyrin Repeat Domain of Human DHHC17 Palmitoyltransferase.34
288828952017Peptide array-based screening reveals a large number of proteins interacting with the ankyrin-repeat domain of the zDHHC17 S-acyltransferase.17
287571452017Structural Basis for Substrate Recognition by the Ankyrin Repeat Domain of Human DHHC17 Palmitoyltransferase.34
288828952017Peptide array-based screening reveals a large number of proteins interacting with the ankyrin-repeat domain of the zDHHC17 S-acyltransferase.17
258499182015Aberrant palmitoylation in Huntington disease.16
276116752015Chlamydia pneumoniae CPj0783 interaction with Huntingtin-protein14.2
258499182015Aberrant palmitoylation in Huntington disease.16
276116752015Chlamydia pneumoniae CPj0783 interaction with Huntingtin-protein14.2
246513842014Identification of binding sites in Huntingtin for the Huntingtin Interacting Proteins HIP14 and HIP14L.12
247053542014The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease.33
246513842014Identification of binding sites in Huntingtin for the Huntingtin Interacting Proteins HIP14 and HIP14L.12
247053542014The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease.33
240017712013DHHC17 palmitoylates ClipR-59 and modulates ClipR-59 association with the plasma membrane.20

Citation

Dessen P

ZDHHC17 (zinc finger DHHC-type palmitoyltransferase 17)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46045/deep-insight-explorer/favicon/manifest.json