Identity
HGNC
LOCATION
16p13.12
LOCUSID
ALIAS
GXPLA2,GXSPLA2,SPLA2,sPLA2-X
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8399
MIM: 603603
HGNC: 9029
Ensembl: ENSG00000069764
Variants:
dbSNP: 8399
ClinVar: 8399
TCGA: ENSG00000069764
COSMIC: PLA2G10
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000069764 | ENST00000438167 | O15496 |
| ENSG00000069764 | ENST00000567462 | H3BRW4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38669316 | 2024 | Up-regulated PLA2G10 in cancer impairs T cell infiltration to dampen immunity. | 0 |
| 38669316 | 2024 | Up-regulated PLA2G10 in cancer impairs T cell infiltration to dampen immunity. | 0 |
| 35231479 | 2022 | PLA2G10 incorporated in exosomes could be diagnostic and prognostic biomarker for non-small cell lung cancer. | 13 |
| 35231479 | 2022 | PLA2G10 incorporated in exosomes could be diagnostic and prognostic biomarker for non-small cell lung cancer. | 13 |
| 32423798 | 2020 | PLA2G10 facilitates the cell-cycle progression of soft tissue leiomyosarcoma cells at least by elevating cyclin E1/CDK2 expression. | 10 |
| 32423798 | 2020 | PLA2G10 facilitates the cell-cycle progression of soft tissue leiomyosarcoma cells at least by elevating cyclin E1/CDK2 expression. | 10 |
| 28528433 | 2017 | Hydrolysis of Phosphatidylcholine-Isoprostanes (PtdCho-IP) by Peripheral Human Group IIA, V and X Secretory Phospholipases A(2) (sPLA(2)). | 2 |
| 28528433 | 2017 | Hydrolysis of Phosphatidylcholine-Isoprostanes (PtdCho-IP) by Peripheral Human Group IIA, V and X Secretory Phospholipases A(2) (sPLA(2)). | 2 |
| 26139511 | 2016 | Endogenous secreted phospholipase A2 group X regulates cysteinyl leukotrienes synthesis by human eosinophils. | 11 |
| 26711221 | 2016 | Hydrolysis of lipoproteins by sPLA2's enhances mitogenesis and eicosanoid release from vascular smooth muscle cells: Diverse activity of sPLA2's IIA, V and X. | 3 |
| 26828067 | 2016 | Group X Secreted Phospholipase A2 Releases ω3 Polyunsaturated Fatty Acids, Suppresses Colitis, and Promotes Sperm Fertility. | 25 |
| 26139511 | 2016 | Endogenous secreted phospholipase A2 group X regulates cysteinyl leukotrienes synthesis by human eosinophils. | 11 |
| 26711221 | 2016 | Hydrolysis of lipoproteins by sPLA2's enhances mitogenesis and eicosanoid release from vascular smooth muscle cells: Diverse activity of sPLA2's IIA, V and X. | 3 |
| 26828067 | 2016 | Group X Secreted Phospholipase A2 Releases ω3 Polyunsaturated Fatty Acids, Suppresses Colitis, and Promotes Sperm Fertility. | 25 |
| 25583995 | 2015 | PLA2G10 Gene Variants, sPLA2 Activity, and Coronary Heart Disease Risk. | 8 |
Citation
Dessen P
PLA2G10 (phospholipase A2 group X)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46060/pla2g10
