DISC1 (DISC1 scaffold protein)

2007-02-01  

Identity

HGNC
LOCATION
1q42.2
LOCUSID
ALIAS
C1orf136,SCZD9
FUSION GENES

Other Information

Locus ID:

NCBI: 27185
MIM: 605210
HGNC: 2888
Ensembl: ENSG00000162946

Variants:

dbSNP: 27185
ClinVar: 27185
TCGA: ENSG00000162946
COSMIC: DISC1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162946ENST00000295051C4P093
ENSG00000162946ENST00000317586Q9NRI5
ENSG00000162946ENST00000366632C4P092
ENSG00000162946ENST00000366633Q9NRI5
ENSG00000162946ENST00000366636Q9NRI5
ENSG00000162946ENST00000366637Q9NRI5
ENSG00000162946ENST00000422590H0Y7U2
ENSG00000162946ENST00000439617Q9NRI5
ENSG00000162946ENST00000535944C4P0B0
ENSG00000162946ENST00000535983Q9NRI5
ENSG00000162946ENST00000537876C4P0B1
ENSG00000162946ENST00000539444Q9NRI5
ENSG00000162946ENST00000602281Q9NRI5
ENSG00000162946ENST00000602700Q9NRI5
ENSG00000162946ENST00000602713Q9NRI5
ENSG00000162946ENST00000602822Q9NRI5
ENSG00000162946ENST00000602873Q9NRI5
ENSG00000162946ENST00000620189A0A087WYX6
ENSG00000162946ENST00000622252C4P0A0
ENSG00000162946ENST00000628350Q9NRI5

Expression (GTEx)

0
1
2
3
4
5
6
7

References

Pubmed IDYearTitleCitations
368586062023Effects of representative point mutations on dynamic behavior of the DISC1-Ndel1 complex: a molecular dynamics study.0
376685632023Disrupted-in-schizophrenia 1 protein aggregates in cerebrospinal fluid are elevated in patients with first-episode psychosis.2
368586062023Effects of representative point mutations on dynamic behavior of the DISC1-Ndel1 complex: a molecular dynamics study.0
376685632023Disrupted-in-schizophrenia 1 protein aggregates in cerebrospinal fluid are elevated in patients with first-episode psychosis.2
349818092022Effects of DISC1 on Alzheimer's disease cell models assessed by iTRAQ proteomics analysis.3
351653962022Regulation of sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport in the cortico-striatal circuit.0
353617012022The D2R-DISC1 protein complex and associated proteins are altered in schizophrenia and normalized with antipsychotic treatment.4
353670902022Impact of COMT, PRODH and DISC1 Genetic Variants on Cognitive Performance of Patients with Schizophrenia.2
354619782022Disrupted-in-schizophrenia 1 Protein Misassembly Impairs Cognitive Flexibility and Social Behaviors in a Transgenic Rat Model.2
355135272022Combining fMRI and DISC1 gene haplotypes to understand working memory-related brain activity in schizophrenia.0
363973612022The variants in PTPRB, TRAF3IP3, and DISC1 genes were associated with Graves' disease in the Chinese population.1
349818092022Effects of DISC1 on Alzheimer's disease cell models assessed by iTRAQ proteomics analysis.3
351653962022Regulation of sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport in the cortico-striatal circuit.0
353617012022The D2R-DISC1 protein complex and associated proteins are altered in schizophrenia and normalized with antipsychotic treatment.4
353670902022Impact of COMT, PRODH and DISC1 Genetic Variants on Cognitive Performance of Patients with Schizophrenia.2

Citation

Dessen P

DISC1 (DISC1 scaffold protein)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46081/disc1