Identity
HGNC
LOCATION
8q24.13
LOCUSID
ALIAS
DER-1,DER1,derlin-1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79139
MIM: 608813
HGNC: 28454
Ensembl: ENSG00000136986
Variants:
dbSNP: 79139
ClinVar: 79139
TCGA: ENSG00000136986
COSMIC: DERL1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38522486 | 2024 | Derlin-1 promotes diet-induced non-alcoholic fatty liver disease via increasing RIPK3-mediated necroptosis. | 0 |
| 38522486 | 2024 | Derlin-1 promotes diet-induced non-alcoholic fatty liver disease via increasing RIPK3-mediated necroptosis. | 0 |
| 37499886 | 2023 | Derlin-1 ameliorates nonalcoholic hepatic steatosis by promoting ubiquitylation and degradation of FABP1. | 1 |
| 37499886 | 2023 | Derlin-1 ameliorates nonalcoholic hepatic steatosis by promoting ubiquitylation and degradation of FABP1. | 1 |
| 35916080 | 2022 | Circular RNA circTTBK2 facilitates non-small-cell lung cancer malignancy through the miR-873-5p/TEAD1/DERL1 axis. | 2 |
| 36122532 | 2022 | Regulation of Derlin-1-mediated degradation of NADPH oxidase partner p22(phox) by thiol modification. | 2 |
| 35916080 | 2022 | Circular RNA circTTBK2 facilitates non-small-cell lung cancer malignancy through the miR-873-5p/TEAD1/DERL1 axis. | 2 |
| 36122532 | 2022 | Regulation of Derlin-1-mediated degradation of NADPH oxidase partner p22(phox) by thiol modification. | 2 |
| 33658201 | 2021 | The cryo-EM structure of an ERAD protein channel formed by tetrameric human Derlin-1. | 16 |
| 35046954 | 2021 | Derlin-1, as a Potential Early Predictive Biomarker for Nonresponse to Infliximab Treatment in Rheumatoid Arthritis, Is Related to Autophagy. | 3 |
| 33658201 | 2021 | The cryo-EM structure of an ERAD protein channel formed by tetrameric human Derlin-1. | 16 |
| 35046954 | 2021 | Derlin-1, as a Potential Early Predictive Biomarker for Nonresponse to Infliximab Treatment in Rheumatoid Arthritis, Is Related to Autophagy. | 3 |
| 31670413 | 2020 | Derlin-1 exhibits oncogenic activities and indicates an unfavorable prognosis in breast cancer. | 8 |
| 31721721 | 2020 | Derlin-1 functions as a growth promoter in breast cancer. | 6 |
| 31670413 | 2020 | Derlin-1 exhibits oncogenic activities and indicates an unfavorable prognosis in breast cancer. | 8 |
Citation
Dessen P
DERL1 (derlin 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46086/derl1
