TG (thyroglobulin)

2007-02-01  

Identity

HGNC
TG
LOCATION
8q24.22
LOCUSID
7038
ALIAS
AITD3,TGN
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7038
MIM: 188450
HGNC: 11764
Ensembl: ENSG00000042832

Variants:

dbSNP: 7038
ClinVar: 7038
TCGA: ENSG00000042832
COSMIC: TG

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000042832ENST00000220616P01266
ENSG00000042832ENST00000518058H0YBC5
ENSG00000042832ENST00000518108H0YBL4
ENSG00000042832ENST00000518505H0YBJ2
ENSG00000042832ENST00000519178H0YBY1
ENSG00000042832ENST00000519543E7EVM0
ENSG00000042832ENST00000521107H0YBR7
ENSG00000042832ENST00000522797H0YBQ6
ENSG00000042832ENST00000523756H0YB42
ENSG00000042832ENST00000523901E5RG33

Expression (GTEx)

0
1000
2000
3000
4000
5000
6000
7000
8000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Autoimmune thyroid diseaseKEGGko05320
Autoimmune thyroid diseaseKEGGhsa05320
Thyroid hormone synthesisKEGGhsa04918
Thyroid hormone synthesisKEGGko04918

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
365477982023The p.Pro2232Leu variant in the ChEL domain of thyroglobulin gene causes intracellular transport disorder and congenital hypothyroidism.0
370439222023Serum thyroglobulin as a biomarker of iodine excess and thyroid disease occurrence in adults.1
371641492023The p.Cys1281Tyr variant in the hinge module/flap region of thyroglobulin causes intracellular transport disorder and congenital hypothyroidism.0
376903642023Lymph node ratio independently associated with postoperative thyroglobulin levels in papillary thyroid cancer.1
380659082023Diagnostic value of thyroglobulin washout in fine-needle aspiration samples for diagnosis and follow-up of differentiated thyroid cancer.0
365477982023The p.Pro2232Leu variant in the ChEL domain of thyroglobulin gene causes intracellular transport disorder and congenital hypothyroidism.0
370439222023Serum thyroglobulin as a biomarker of iodine excess and thyroid disease occurrence in adults.1
371641492023The p.Cys1281Tyr variant in the hinge module/flap region of thyroglobulin causes intracellular transport disorder and congenital hypothyroidism.0
376903642023Lymph node ratio independently associated with postoperative thyroglobulin levels in papillary thyroid cancer.1
380659082023Diagnostic value of thyroglobulin washout in fine-needle aspiration samples for diagnosis and follow-up of differentiated thyroid cancer.0
348966202022TSH stimulation of human thyroglobulin and thyroid peroxidase gene transcription is partially dependent on internalization.0
350132492022Cryo-EM structure of native human thyroglobulin.5
360125112022Targeted Next-Generation Sequencing of Congenital Hypothyroidism-Causative Genes Reveals Unexpected Thyroglobulin Gene Variants in Patients with Iodide Transport Defect.1
361613012022Clinical features of multifocal papillary thyroid carcinoma and risk factors of cervical metastatic lymph nodes.0
379068182022[Analysis of pre-ablative and preoperative thyroglobulin in differentiated thyroid cancer].0

Citation

Dessen P

TG (thyroglobulin)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46096