Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3710
MIM: 147267
HGNC: 6182
Ensembl: ENSG00000096433
Variants:
dbSNP: 3710
ClinVar: 3710
TCGA: ENSG00000096433
COSMIC: ITPR3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000096433 | ENST00000374316 | Q14573 |
| ENSG00000096433 | ENST00000605930 | Q14573 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36302985 | 2023 | Disrupted Ca(2+) homeostasis and immunodeficiency in patients with functional IP(3) receptor subtype 3 defects. | 5 |
| 36350267 | 2023 | Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population. | 1 |
| 36302985 | 2023 | Disrupted Ca(2+) homeostasis and immunodeficiency in patients with functional IP(3) receptor subtype 3 defects. | 5 |
| 36350267 | 2023 | Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population. | 1 |
| 34798470 | 2022 | Inositol 1,4,5-trisphosphate receptor type 3 (ITPR3) is overexpressed in cholangiocarcinoma and its expression correlates with S100 calcium-binding protein A4 (S100A4). | 2 |
| 34798470 | 2022 | Inositol 1,4,5-trisphosphate receptor type 3 (ITPR3) is overexpressed in cholangiocarcinoma and its expression correlates with S100 calcium-binding protein A4 (S100A4). | 2 |
| 33400994 | 2021 | Potentially functional variants of HBEGF and ITPR3 in GnRH signaling pathway genes predict survival of non-small cell lung cancer patients. | 10 |
| 33573671 | 2021 | ITPR3 facilitates tumor growth, metastasis and stemness by inducing the NF-ĸB/CD44 pathway in urinary bladder carcinoma. | 14 |
| 33400994 | 2021 | Potentially functional variants of HBEGF and ITPR3 in GnRH signaling pathway genes predict survival of non-small cell lung cancer patients. | 10 |
| 33573671 | 2021 | ITPR3 facilitates tumor growth, metastasis and stemness by inducing the NF-ĸB/CD44 pathway in urinary bladder carcinoma. | 14 |
| 31915246 | 2020 | Cryo-EM structure of human type-3 inositol triphosphate receptor reveals the presence of a self-binding peptide that acts as an antagonist. | 12 |
| 31979185 | 2020 | Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells. | 11 |
| 32916960 | 2020 | STIM1 Deficiency Leads to Specific Down-Regulation of ITPR3 in SH-SY5Y Cells. | 6 |
| 32949214 | 2020 | Dominant mutations in ITPR3 cause Charcot-Marie-Tooth disease. | 8 |
| 31915246 | 2020 | Cryo-EM structure of human type-3 inositol triphosphate receptor reveals the presence of a self-binding peptide that acts as an antagonist. | 12 |
Citation
Dessen P
ITPR3 (inositol 1,4,5-trisphosphate receptor type 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46118/itpr3
