Identity
HGNC
LOCATION
17q12
LOCUSID
ALIAS
AIO,AIOLOS,ZNFN1A3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 22806
MIM: 606221
HGNC: 13178
Ensembl: ENSG00000161405
Variants:
dbSNP: 22806
ClinVar: 22806
TCGA: ENSG00000161405
COSMIC: IKZF3
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38015619 | 2024 | Disease-associated AIOLOS variants lead to immune deficiency/dysregulation by haploinsufficiency and redefine AIOLOS functional domains. | 1 |
| 38018448 | 2024 | IKZF3 polymorphisms contribute to the increased risk of acute lymphoblastic leukemia in children. | 0 |
| 38193570 | 2024 | Genetic variations in IKZF3, LET7-a2, and CDKN2B-AS1: Exploring associations with metabolic syndrome susceptibility and clinical manifestations. | 1 |
| 38015619 | 2024 | Disease-associated AIOLOS variants lead to immune deficiency/dysregulation by haploinsufficiency and redefine AIOLOS functional domains. | 1 |
| 38018448 | 2024 | IKZF3 polymorphisms contribute to the increased risk of acute lymphoblastic leukemia in children. | 0 |
| 38193570 | 2024 | Genetic variations in IKZF3, LET7-a2, and CDKN2B-AS1: Exploring associations with metabolic syndrome susceptibility and clinical manifestations. | 1 |
| 36930079 | 2023 | IKZF3 is a novel prognostic biomarker for head and neck squamous cell carcinoma: A study based on bioinformatics analysis. | 1 |
| 36930079 | 2023 | IKZF3 is a novel prognostic biomarker for head and neck squamous cell carcinoma: A study based on bioinformatics analysis. | 1 |
| 34687790 | 2022 | IKZF3 deficiency potentiates chimeric antigen receptor T cells targeting solid tumors. | 13 |
| 35444653 | 2022 | AIOLOS Variants Causing Immunodeficiency in Human and Mice. | 3 |
| 36180600 | 2022 | IKZF3 amplification frequently occurs in HER2-positive breast cancer and is a potential therapeutic target. | 1 |
| 34687790 | 2022 | IKZF3 deficiency potentiates chimeric antigen receptor T cells targeting solid tumors. | 13 |
| 35444653 | 2022 | AIOLOS Variants Causing Immunodeficiency in Human and Mice. | 3 |
| 36180600 | 2022 | IKZF3 amplification frequently occurs in HER2-positive breast cancer and is a potential therapeutic target. | 1 |
| 33499314 | 2021 | Role of Aiolos and Ikaros in the Antitumor and Immunomodulatory Activity of IMiDs in Multiple Myeloma: Better to Lose Than to Find Them. | 10 |
Citation
Dessen P
IKZF3 (IKAROS family zinc finger 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46122/ikzf3
