CYGB (cytoglobin)

2007-02-01  

Identity

HGNC
CYGB
LOCATION
17q25.1
LOCUSID
114757
ALIAS
HGB,STAP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 114757
MIM: 608759
HGNC: 16505
Ensembl: ENSG00000161544

Variants:

dbSNP: 114757
ClinVar: 114757
TCGA: ENSG00000161544
COSMIC: CYGB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000161544ENST00000293230Q8WWM9
ENSG00000161544ENST00000293230A0A1K0FUB6
ENSG00000161544ENST00000589145K7EIM9
ENSG00000161544ENST00000589342K7EMC7
ENSG00000161544ENST00000590175K7EIM9

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of nitric oxideREACTOMER-HSA-202131
eNOS activation and regulationREACTOMER-HSA-203765
eNOS activationREACTOMER-HSA-203615

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
336118112021Cytoglobin promotes sensitivity to ferroptosis by regulating p53-YAP1 axis in colon cancer cells.32
340353732021A reliable set of reference genes to normalize oxygen-dependent cytoglobin gene expression levels in melanoma.10
346294502021Cytoglobin as a Prognostic Factor for Pancreatic Ductal Adenocarcinoma: A Retrospective Analysis of 75 Patients.0
349308342021Cytoglobin has potent superoxide dismutase function.12
336118112021Cytoglobin promotes sensitivity to ferroptosis by regulating p53-YAP1 axis in colon cancer cells.32
340353732021A reliable set of reference genes to normalize oxygen-dependent cytoglobin gene expression levels in melanoma.10
346294502021Cytoglobin as a Prognostic Factor for Pancreatic Ductal Adenocarcinoma: A Retrospective Analysis of 75 Patients.0
349308342021Cytoglobin has potent superoxide dismutase function.12
318801652020Regulation of Nitric Oxide Metabolism and Vascular Tone by Cytoglobin.18
319100472020The Antioxidative Role of Cytoglobin in Podocytes: Implications for a Role in Chronic Kidney Disease.16
323306052020TGF-β1-driven reduction of cytoglobin leads to oxidative DNA damage in stellate cells during non-alcoholic steatohepatitis.17
329455242020Cytoglobin-expressing cells in the splenic cords contribute to splenic fibrosis in cirrhotic patients.1
318801652020Regulation of Nitric Oxide Metabolism and Vascular Tone by Cytoglobin.18
319100472020The Antioxidative Role of Cytoglobin in Podocytes: Implications for a Role in Chronic Kidney Disease.16
323306052020TGF-β1-driven reduction of cytoglobin leads to oxidative DNA damage in stellate cells during non-alcoholic steatohepatitis.17

Citation

Dessen P

CYGB (cytoglobin)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46125/case-report-explorer/favicon/favicon/favicon-32x32.png