CYGB (cytoglobin)

2007-02-01  

Identity

HGNC
LOCATION
17q25.1
LOCUSID
ALIAS
HGB,STAP
FUSION GENES

Other Information

Locus ID:

NCBI: 114757
MIM: 608759
HGNC: 16505
Ensembl: ENSG00000161544

Variants:

dbSNP: 114757
ClinVar: 114757
TCGA: ENSG00000161544
COSMIC: CYGB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000161544ENST00000293230Q8WWM9
ENSG00000161544ENST00000293230A0A1K0FUB6
ENSG00000161544ENST00000589145K7EIM9
ENSG00000161544ENST00000589342K7EMC7
ENSG00000161544ENST00000590175K7EIM9

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of nitric oxideREACTOMER-HSA-202131
eNOS activation and regulationREACTOMER-HSA-203765
eNOS activationREACTOMER-HSA-203615

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
336118112021Cytoglobin promotes sensitivity to ferroptosis by regulating p53-YAP1 axis in colon cancer cells.32
340353732021A reliable set of reference genes to normalize oxygen-dependent cytoglobin gene expression levels in melanoma.10
346294502021Cytoglobin as a Prognostic Factor for Pancreatic Ductal Adenocarcinoma: A Retrospective Analysis of 75 Patients.0
349308342021Cytoglobin has potent superoxide dismutase function.12
336118112021Cytoglobin promotes sensitivity to ferroptosis by regulating p53-YAP1 axis in colon cancer cells.32
340353732021A reliable set of reference genes to normalize oxygen-dependent cytoglobin gene expression levels in melanoma.10
346294502021Cytoglobin as a Prognostic Factor for Pancreatic Ductal Adenocarcinoma: A Retrospective Analysis of 75 Patients.0
349308342021Cytoglobin has potent superoxide dismutase function.12
318801652020Regulation of Nitric Oxide Metabolism and Vascular Tone by Cytoglobin.18
319100472020The Antioxidative Role of Cytoglobin in Podocytes: Implications for a Role in Chronic Kidney Disease.16
323306052020TGF-β1-driven reduction of cytoglobin leads to oxidative DNA damage in stellate cells during non-alcoholic steatohepatitis.17
329455242020Cytoglobin-expressing cells in the splenic cords contribute to splenic fibrosis in cirrhotic patients.1
318801652020Regulation of Nitric Oxide Metabolism and Vascular Tone by Cytoglobin.18
319100472020The Antioxidative Role of Cytoglobin in Podocytes: Implications for a Role in Chronic Kidney Disease.16
323306052020TGF-β1-driven reduction of cytoglobin leads to oxidative DNA damage in stellate cells during non-alcoholic steatohepatitis.17

Citation

Dessen P

CYGB (cytoglobin)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46125/deep-insight-explorer/gene-fusions/js/template.js