Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 623
MIM: 600337
HGNC: 1029
Ensembl: ENSG00000100739
Variants:
dbSNP: 623
ClinVar: 623
TCGA: ENSG00000100739
COSMIC: BDKRB1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000100739 | ENST00000216629 | P46663 |
| ENSG00000100739 | ENST00000553356 | G3V4Y2 |
| ENSG00000100739 | ENST00000611804 | P46663 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443796 | Coronary Artery Disease | Disease | ClinicalAnnotation | associated | PD | 20712529 | |
| PA450877 | perindopril | Chemical | ClinicalAnnotation | associated | PD | 20712529 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37703419 | 2024 | Bradykinin receptor expression and bradykinin-mediated sensitization of human sensory neurons. | 4 |
| 37703419 | 2024 | Bradykinin receptor expression and bradykinin-mediated sensitization of human sensory neurons. | 4 |
| 37818853 | 2023 | Bradykinin-bradykinin receptor (B1R) signalling is involved in the blood-brain barrier disruption in moyamoya disease. | 1 |
| 37818853 | 2023 | Bradykinin-bradykinin receptor (B1R) signalling is involved in the blood-brain barrier disruption in moyamoya disease. | 1 |
| 36142237 | 2022 | The Role of Bradykinin Receptors in Hereditary Angioedema Due to C1-Inhibitor Deficiency. | 1 |
| 36142237 | 2022 | The Role of Bradykinin Receptors in Hereditary Angioedema Due to C1-Inhibitor Deficiency. | 1 |
| 33284471 | 2021 | Correlation of matrix-related airway remodeling and bradykinin B1 receptor expression with fixed airflow obstruction in severe asthma. | 5 |
| 33284471 | 2021 | Correlation of matrix-related airway remodeling and bradykinin B1 receptor expression with fixed airflow obstruction in severe asthma. | 5 |
| 32087235 | 2020 | Kinin B1 receptor: A target for neuroinflammation in hypertension. | 17 |
| 32087235 | 2020 | Kinin B1 receptor: A target for neuroinflammation in hypertension. | 17 |
| 30132865 | 2019 | Antitumor activity of cell-penetrant kinin B1 receptor antagonists in human triple-negative breast cancer cells. | 0 |
| 30366000 | 2019 | Bradykinin B1 receptor contributes to interleukin-8 production and glioblastoma migration through interaction of STAT3 and SP-1. | 18 |
| 31017477 | 2019 | The G Allele of the rs12050217 Polymorphism in the BDKRB1 Gene Is Associated with Protection for Diabetic Retinopathy. | 0 |
| 31218444 | 2019 | Interactions between carboxypeptidase M and kinin B1 receptor in endothelial cells. | 4 |
| 30132865 | 2019 | Antitumor activity of cell-penetrant kinin B1 receptor antagonists in human triple-negative breast cancer cells. | 0 |
Citation
Dessen P
BDKRB1 (bradykinin receptor B1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46143/bdkrb1
