TGIF1 (TGFB induced factor homeobox 1)

2007-02-01  

Identity

HGNC
TGIF1
LOCATION
18p11.31
LOCUSID
7050
ALIAS
HPE4,TGIF
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7050
MIM: 602630
HGNC: 11776
Ensembl: ENSG00000177426

Variants:

dbSNP: 7050
ClinVar: 7050
TCGA: ENSG00000177426
COSMIC: TGIF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000177426ENST00000330513Q15583
ENSG00000177426ENST00000343820Q15583
ENSG00000177426ENST00000345133Q15583
ENSG00000177426ENST00000400167Q15583
ENSG00000177426ENST00000401449Q15583
ENSG00000177426ENST00000405385Q15583
ENSG00000177426ENST00000407501Q15583
ENSG00000177426ENST00000472042Q15583
ENSG00000177426ENST00000546979F8VYL4
ENSG00000177426ENST00000548489Q15583
ENSG00000177426ENST00000549253F8VXG3
ENSG00000177426ENST00000549468F8VX54
ENSG00000177426ENST00000549546F8VVS9
ENSG00000177426ENST00000549780F8VUY0
ENSG00000177426ENST00000550958F8VW34
ENSG00000177426ENST00000551333F8VZH2
ENSG00000177426ENST00000551402F8W1J9
ENSG00000177426ENST00000551541Q15583
ENSG00000177426ENST00000552383F8VWK5
ENSG00000177426ENST00000577543J3KS32
ENSG00000177426ENST00000618001Q15583

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
TGF-beta signaling pathwayKEGGko04350
TGF-beta signaling pathwayKEGGhsa04350
Signal TransductionREACTOMER-HSA-162582
Signaling by TGF-beta Receptor ComplexREACTOMER-HSA-170834
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimerREACTOMER-HSA-2173793
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcriptionREACTOMER-HSA-2173796
Downregulation of SMAD2/3:SMAD4 transcriptional activityREACTOMER-HSA-2173795
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436

References

Pubmed IDYearTitleCitations
385751072024TG-interacting factor 1 regulates mitotic clonal expansion during adipocyte differentiation.0
385751072024TG-interacting factor 1 regulates mitotic clonal expansion during adipocyte differentiation.0
377161272023Genetic polymorphisms of rs73620203 in the transforming growth interacting factor gene associated with rheumatoid arthritis in a Chinese population.0
377161272023Genetic polymorphisms of rs73620203 in the transforming growth interacting factor gene associated with rheumatoid arthritis in a Chinese population.0
355691222022TGIF1 overexpression promotes glioma progression and worsens patient prognosis.6
355691222022TGIF1 overexpression promotes glioma progression and worsens patient prognosis.6
336939542021TGIF1 plays a carcinogenic role in esophageal squamous cell carcinoma through the Wnt/β‑catenin and Akt/mTOR signaling pathways.1
343913992021TGFB-induced factor homeobox 1 (TGIF) expression in breast cancer.1
344403022021Allelic Variants in Established Hypopituitarism Genes Expand Our Knowledge of the Phenotypic Spectrum.0
348844562021Structural Insight into the Binding of TGIF1 to SIN3A PAH2 Domain through a C-Terminal Amphipathic Helix.2
336939542021TGIF1 plays a carcinogenic role in esophageal squamous cell carcinoma through the Wnt/β‑catenin and Akt/mTOR signaling pathways.1
343913992021TGFB-induced factor homeobox 1 (TGIF) expression in breast cancer.1
344403022021Allelic Variants in Established Hypopituitarism Genes Expand Our Knowledge of the Phenotypic Spectrum.0
348844562021Structural Insight into the Binding of TGIF1 to SIN3A PAH2 Domain through a C-Terminal Amphipathic Helix.2
321965922020XTP8 stimulates migration and invasion of gastric carcinoma through interacting with TGIF1.3

Citation

Dessen P

TGIF1 (TGFB induced factor homeobox 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46146