HOXA1 (homeobox A1)

2007-02-01  

Identity

HGNC
HOXA1
LOCATION
7p15.2
LOCUSID
3198
ALIAS
BSAS,HOX1,HOX1F
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 3198
MIM: 142955
HGNC: 5099
Ensembl: ENSG00000105991

Variants:

dbSNP: 3198
ClinVar: 3198
TCGA: ENSG00000105991
COSMIC: HOXA1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105991ENST00000355633E7ERT8
ENSG00000105991ENST00000643460A0A2R8Y4R9

Expression (GTEx)

0
1
2
3
4
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
Activation of HOX genes during differentiationREACTOMER-HSA-5619507
Activation of anterior HOX genes in hindbrain development during early embryogenesisREACTOMER-HSA-5617472

References

Pubmed IDYearTitleCitations
379230542024Downregulation of homeobox A1 in human granulosa cells is involved in diminished ovarian reserve through promoting cell apoptosis and mitochondrial dysfunction.1
379525722024A poly-histidine motif of HOXA1 is involved in regulatory interactions with cysteine-rich proteins.0
384779422024HOXA1 silencing inhibits cisplatin resistance of oral squamous cell carcinoma cells via IκB/NF-κB signaling pathway.0
379230542024Downregulation of homeobox A1 in human granulosa cells is involved in diminished ovarian reserve through promoting cell apoptosis and mitochondrial dysfunction.1
379525722024A poly-histidine motif of HOXA1 is involved in regulatory interactions with cysteine-rich proteins.0
384779422024HOXA1 silencing inhibits cisplatin resistance of oral squamous cell carcinoma cells via IκB/NF-κB signaling pathway.0
367299772023Circ_0058063 regulates the development of esophageal cancer through miR-377-3p/HOXA1 axis.1
372861202023HOXA1 promotes aerobic glycolysis and cancer progression in cervical cancer.3
367299772023Circ_0058063 regulates the development of esophageal cancer through miR-377-3p/HOXA1 axis.1
372861202023HOXA1 promotes aerobic glycolysis and cancer progression in cervical cancer.3
347998752022Hsa_circ_0074032 promotes prostate cancer progression through elevating homeobox A1 expression by serving as a microRNA-198 decoy.2
356758572022HOXA1, a breast cancer oncogene.2
362283472022HOXA1 promotes proliferation and metastasis of bladder cancer by enhancing SMAD3 transcription.4
347998752022Hsa_circ_0074032 promotes prostate cancer progression through elevating homeobox A1 expression by serving as a microRNA-198 decoy.2
356758572022HOXA1, a breast cancer oncogene.2

Citation

Dessen P

HOXA1 (homeobox A1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46150