Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4931
MIM: 602426
HGNC: 8070
Ensembl: ENSG00000143748
Variants:
dbSNP: 4931
ClinVar: 4931
TCGA: ENSG00000143748
COSMIC: NVL
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Ribosome biogenesis in eukaryotes | KEGG | ko03008 |
| Ribosome biogenesis in eukaryotes | KEGG | hsa03008 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33422691 | 2021 | Interactome analysis of the Tudor domain-containing protein SPF30 which associates with the MTR4-exosome RNA-decay machinery under the regulation of AAA-ATPase NVL2. | 2 |
| 33422691 | 2021 | Interactome analysis of the Tudor domain-containing protein SPF30 which associates with the MTR4-exosome RNA-decay machinery under the regulation of AAA-ATPase NVL2. | 2 |
| 31358741 | 2019 | The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs. | 25 |
| 31358741 | 2019 | The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs. | 25 |
| 29107693 | 2018 | WDR74 participates in an early cleavage of the pre-rRNA processing pathway in cooperation with the nucleolar AAA-ATPase NVL2. | 12 |
| 29107693 | 2018 | WDR74 participates in an early cleavage of the pre-rRNA processing pathway in cooperation with the nucleolar AAA-ATPase NVL2. | 12 |
| 25891250 | 2015 | The NVL gene confers risk for both major depressive disorder and schizophrenia in the Han Chinese population. | 7 |
| 26166824 | 2015 | NVL2, a nucleolar AAA-ATPase, is associated with the nuclear exosome and is involved in pre-rRNA processing. | 11 |
| 26456651 | 2015 | AAA-ATPase NVL2 acts on MTR4-exosome complex to dissociate the nucleolar protein WDR74. | 12 |
| 25891250 | 2015 | The NVL gene confers risk for both major depressive disorder and schizophrenia in the Han Chinese population. | 7 |
| 26166824 | 2015 | NVL2, a nucleolar AAA-ATPase, is associated with the nuclear exosome and is involved in pre-rRNA processing. | 11 |
| 26456651 | 2015 | AAA-ATPase NVL2 acts on MTR4-exosome complex to dissociate the nucleolar protein WDR74. | 12 |
| 22226966 | 2012 | The AAA-ATPase NVL2 is a telomerase component essential for holoenzyme assembly. | 15 |
| 22226966 | 2012 | The AAA-ATPase NVL2 is a telomerase component essential for holoenzyme assembly. | 15 |
| 21474449 | 2011 | Structure and function of the N-terminal nucleolin binding domain of nuclear valosin-containing protein-like 2 (NVL2) harboring a nucleolar localization signal. | 15 |
Citation
Dessen P
NVL (nuclear VCP like)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46210
