CCL22 (C-C motif chemokine ligand 22)

2007-02-01  

Identity

HGNC
LOCATION
16q21
LOCUSID
ALIAS
A-152E5.1,ABCD-1,DC/B-CK,MDC,SCYA22,STCP-1
FUSION GENES

Other Information

Locus ID:

NCBI: 6367
MIM: 602957
HGNC: 10621
Ensembl: ENSG00000102962

Variants:

dbSNP: 6367
ClinVar: 6367
TCGA: ENSG00000102962
COSMIC: CCL22

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102962ENST00000219235O00626

Expression (GTEx)

0
100
200
300
400
500
600
700

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Cytokine-cytokine receptor interactionKEGGhsa04060
Chemokine signaling pathwayKEGGko04062
Chemokine signaling pathwayKEGGhsa04062
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Signaling by InterleukinsREACTOMER-HSA-449147
Interleukin-4 and 13 signalingREACTOMER-HSA-6785807
Interleukin-10 signalingREACTOMER-HSA-6783783

References

Pubmed IDYearTitleCitations
383872812024Tumor-associated macrophage (TAM)-secreted CCL22 confers cisplatin resistance of esophageal squamous cell carcinoma (ESCC) cells via regulating the activity of diacylglycerol kinase α (DGKα)/NOX4 axis.0
389244142024Macrophage-derived chemokine CCL22 establishes local LN-mediated adaptive thermogenesis and energy expenditure.0
383872812024Tumor-associated macrophage (TAM)-secreted CCL22 confers cisplatin resistance of esophageal squamous cell carcinoma (ESCC) cells via regulating the activity of diacylglycerol kinase α (DGKα)/NOX4 axis.0
389244142024Macrophage-derived chemokine CCL22 establishes local LN-mediated adaptive thermogenesis and energy expenditure.0
367928112023Increase of the T-reg-recruiting chemokine CCL22 expression in a progressive course of cervical dysplasia.1
371247252023CCL17 and CCL22 chemokines are upregulated in human obesity and play a role in vascular dysfunction.1
376858902023Macrophage-Derived Chemokine MDC/CCL22: An Ambiguous Finding in COVID-19.2
367928112023Increase of the T-reg-recruiting chemokine CCL22 expression in a progressive course of cervical dysplasia.1
371247252023CCL17 and CCL22 chemokines are upregulated in human obesity and play a role in vascular dysfunction.1
376858902023Macrophage-Derived Chemokine MDC/CCL22: An Ambiguous Finding in COVID-19.2
359621912022Tumor-associated macrophage (TAM)-derived CCL22 induces FAK addiction in esophageal squamous cell carcinoma (ESCC).12
362240142022Spatial Transcriptomics Analysis Reveals that CCL17 and CCL22 are Robust Indicators of a Suppressive Immune Environment in Angioimmunoblastic T Cell Lymphoma (AITL).2
359621912022Tumor-associated macrophage (TAM)-derived CCL22 induces FAK addiction in esophageal squamous cell carcinoma (ESCC).12
362240142022Spatial Transcriptomics Analysis Reveals that CCL17 and CCL22 are Robust Indicators of a Suppressive Immune Environment in Angioimmunoblastic T Cell Lymphoma (AITL).2
324804262021Systematic reassessment of chemokine-receptor pairings confirms CCL20 but not CXCL13 and extends the spectrum of ACKR4 agonists to CCL22.6

Citation

Dessen P

CCL22 (C-C motif chemokine ligand 22)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46211/ccl22