CIZ1 (CDKN1A interacting zinc finger protein 1)

2007-02-01  

Identity

HGNC
CIZ1
LOCATION
9q34.11
LOCUSID
25792
ALIAS
LSFR1,NP94,ZNF356
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 25792
MIM: 611420
HGNC: 16744
Ensembl: ENSG00000148337

Variants:

dbSNP: 25792
ClinVar: 25792
TCGA: ENSG00000148337
COSMIC: CIZ1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000148337ENST00000277465Q5SYW2
ENSG00000148337ENST00000324544F6VD24
ENSG00000148337ENST00000357558Q5SYW2
ENSG00000148337ENST00000372938Q9ULV3
ENSG00000148337ENST00000372938A0A024R885
ENSG00000148337ENST00000372948Q9ULV3
ENSG00000148337ENST00000372954Q9ULV3
ENSG00000148337ENST00000393608Q9BTG3
ENSG00000148337ENST00000415526H0Y5D5
ENSG00000148337ENST00000420484F6WSM2
ENSG00000148337ENST00000471839A0A0U1RQR2
ENSG00000148337ENST00000538431F5H2X7
ENSG00000148337ENST00000629610Q9ULV3
ENSG00000148337ENST00000634901Q9ULV3
ENSG00000148337ENST00000634901A0A024R885
ENSG00000148337ENST00000651955A0A494C0L7

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
321966042020Upregulation of lncRNA DANCR functions as an oncogenic role in non-small lung cancer by regulating miR-214-5p/CIZ1 axis.16
321966042020Upregulation of lncRNA DANCR functions as an oncogenic role in non-small lung cancer by regulating miR-214-5p/CIZ1 axis.16
304565332019CIZ1 Expression Is Upregulated in Hemangioma of the Tongue.1
312521642019CIZ1 knockdown suppresses the proliferation of bladder cancer cells by inducing apoptosis.6
304565332019CIZ1 Expression Is Upregulated in Hemangioma of the Tongue.1
312521642019CIZ1 knockdown suppresses the proliferation of bladder cancer cells by inducing apoptosis.6
289239642017Repeat E anchors Xist RNA to the inactive X chromosomal compartment through CDKN1A-interacting protein (CIZ1).55
289239642017Repeat E anchors Xist RNA to the inactive X chromosomal compartment through CDKN1A-interacting protein (CIZ1).55
265153352016CIZ1 is upregulated in hepatocellular carcinoma and promotes the growth and migration of the cancer cells.11
269065522016CIZ1 interacts with YAP and activates its transcriptional activity in hepatocellular carcinoma cells.9
265153352016CIZ1 is upregulated in hepatocellular carcinoma and promotes the growth and migration of the cancer cells.11
269065522016CIZ1 interacts with YAP and activates its transcriptional activity in hepatocellular carcinoma cells.9
254276412015CIZ1 promoted the growth and migration of gallbladder cancer cells.14
257362922015Cyclin-A-CDK2-mediated phosphorylation of CIZ1 blocks replisome formation and initiation of mammalian DNA replication.20
257787062015Mutations in CIZ1 are not a major cause for dystonia in Germany.4

Citation

Dessen P

CIZ1 (CDKN1A interacting zinc finger protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46240/js/case-report-explorer/favicon/apple-touch-icon.png