GSC (goosecoid homeobox)

2007-02-01  

Identity

HGNC
GSC
LOCATION
14q32.13
LOCUSID
145258
ALIAS
SAMS

Other Information

Locus ID:

NCBI: 145258
MIM: 138890
HGNC: 4612
Ensembl: ENSG00000133937

Variants:

dbSNP: 145258
ClinVar: 145258
TCGA: ENSG00000133937
COSMIC: GSC

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000133937ENST00000238558P56915

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
312536982019USP21 modulates Goosecoid function through deubiquitination.3
312536982019USP21 modulates Goosecoid function through deubiquitination.3
281095042017Mutational analysis of GSC, HOXA2 and PRKRA in 106 Chinese patients with microtia.4
281095042017Mutational analysis of GSC, HOXA2 and PRKRA in 106 Chinese patients with microtia.4
275262422016Mutational Analysis of TCOF1, GSC, and HOXA2 in Patients With Treacher Collins Syndrome.1
277057852016DIGIT Is a Conserved Long Noncoding RNA that Regulates GSC Expression to Control Definitive Endoderm Differentiation of Embryonic Stem Cells.37
275262422016Mutational Analysis of TCOF1, GSC, and HOXA2 in Patients With Treacher Collins Syndrome.1
277057852016DIGIT Is a Conserved Long Noncoding RNA that Regulates GSC Expression to Control Definitive Endoderm Differentiation of Embryonic Stem Cells.37
233781412014Chronic ethanol exposure increases goosecoid (GSC) expression in human embryonic carcinoma cell differentiation.4
248585672014Overexpression of goosecoid homeobox is associated with chemoresistance and poor prognosis in ovarian carcinoma.17
253433362014Goosecoid promotes the metastasis of hepatocellular carcinoma by modulating the epithelial-mesenchymal transition.17
233781412014Chronic ethanol exposure increases goosecoid (GSC) expression in human embryonic carcinoma cell differentiation.4
248585672014Overexpression of goosecoid homeobox is associated with chemoresistance and poor prognosis in ovarian carcinoma.17
253433362014Goosecoid promotes the metastasis of hepatocellular carcinoma by modulating the epithelial-mesenchymal transition.17
242903752013SAMS, a syndrome of short stature, auditory-canal atresia, mandibular hypoplasia, and skeletal abnormalities is a unique neurocristopathy caused by mutations in Goosecoid.21

Citation

Dessen P

GSC (goosecoid homeobox)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46257