Identity
HGNC
LOCATION
9q21.11
LOCUSID
ALIAS
CyaY,FA,FARR,FRDA,X25
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2395
MIM: 606829
HGNC: 3951
Ensembl: ENSG00000165060
Variants:
dbSNP: 2395
ClinVar: 2395
TCGA: ENSG00000165060
COSMIC: FXN
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38266318 | 2024 | Protective effect of FXN overexpression on ferroptosis in L-Glu-induced SH-SY5Y cells. | 3 |
| 38396238 | 2024 | Phenotypic variation of FXN compound heterozygotes in a Friedreich ataxia cohort. | 0 |
| 38552947 | 2024 | The Mechanism of Folding of Human Frataxin in Comparison to the Yeast Homologue - Broad Energy Barriers and the General Properties of the Transition State. | 0 |
| 38891993 | 2024 | An In Silico Analysis of Genetic Variants and Structural Modeling of the Human Frataxin Protein in Friedreich's Ataxia. | 0 |
| 38920668 | 2024 | The Regulation of the Disease-Causing Gene FXN. | 0 |
| 38266318 | 2024 | Protective effect of FXN overexpression on ferroptosis in L-Glu-induced SH-SY5Y cells. | 3 |
| 38396238 | 2024 | Phenotypic variation of FXN compound heterozygotes in a Friedreich ataxia cohort. | 0 |
| 38552947 | 2024 | The Mechanism of Folding of Human Frataxin in Comparison to the Yeast Homologue - Broad Energy Barriers and the General Properties of the Transition State. | 0 |
| 38891993 | 2024 | An In Silico Analysis of Genetic Variants and Structural Modeling of the Human Frataxin Protein in Friedreich's Ataxia. | 0 |
| 38920668 | 2024 | The Regulation of the Disease-Causing Gene FXN. | 0 |
| 36369844 | 2023 | Frataxin deficiency alters gene expression in Friedreich ataxia derived IPSC-neurons and cardiomyocytes. | 2 |
| 36550598 | 2023 | Astrocytic mitochondrial frataxin-A promising target for ischemic brain injury. | 2 |
| 36635061 | 2023 | FXN gene methylation determines carrier status in Friedreich ataxia. | 0 |
| 38062036 | 2023 | Human frataxin, the Friedreich ataxia deficient protein, interacts with mitochondrial respiratory chain. | 2 |
| 36369844 | 2023 | Frataxin deficiency alters gene expression in Friedreich ataxia derived IPSC-neurons and cardiomyocytes. | 2 |
Citation
Dessen P
FXN (frataxin)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46262/fxn
