GSX2 (GS homeobox 2)

2007-02-01 Affiliation

Identity

HGNC

GSX2

LOCATION

4q12

LOCUSID

170825

ALIAS

DMJDS2,GSH2

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 170825
MIM: 616253
HGNC: 24959
Ensembl: ENSG00000180613

Variants:

dbSNP: 170825
ClinVar: 170825
TCGA: ENSG00000180613
COSMIC: GSX2

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000180613	ENST00000326902	Q9BZM3
ENSG00000180613	ENST00000503800	D6R903

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
34623580	2022	Silencing GS Homeobox 2 Alleviates Gemcitabine Resistance in Pancreatic Cancer Cells by Activating SHH/GLI1 Signaling Pathway.	3
34623580	2022	Silencing GS Homeobox 2 Alleviates Gemcitabine Resistance in Pancreatic Cancer Cells by Activating SHH/GLI1 Signaling Pathway.	3
29794476	2018	Integrative Analysis of DNA Methylation and Gene Expression Identify a Three-Gene Signature for Predicting Prognosis in Lower-Grade Gliomas.	33
29794476	2018	Integrative Analysis of DNA Methylation and Gene Expression Identify a Three-Gene Signature for Predicting Prognosis in Lower-Grade Gliomas.	33
28137879	2017	Differentiation of human telencephalic progenitor cells into MSNs by inducible expression of Gsx2 and Ebf1.	16
28137879	2017	Differentiation of human telencephalic progenitor cells into MSNs by inducible expression of Gsx2 and Ebf1.	16
25816740	2015	4q12 translocations with GSX2 expression identify a CD7(+) acute myeloid leukaemia subset.	3
25816740	2015	4q12 translocations with GSX2 expression identify a CD7(+) acute myeloid leukaemia subset.	3
22242181	2012	The homeobox gene Gsx2 regulates the self-renewal and differentiation of neural stem cells and the cell fate of postnatal progenitors.	13
22242181	2012	The homeobox gene Gsx2 regulates the self-renewal and differentiation of neural stem cells and the cell fate of postnatal progenitors.	13
21368052	2011	MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors.	177
21368052	2011	MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors.	177
19709628	2009	Distinct temporal requirements for the homeobox gene Gsx2 in specifying striatal and olfactory bulb neuronal fates.	77
19709628	2009	Distinct temporal requirements for the homeobox gene Gsx2 in specifying striatal and olfactory bulb neuronal fates.	77
11861295	2002	Evidence for position effects as a variant ETV6-mediated leukemogenic mechanism in myeloid leukemias with a t(4;12)(q11-q12;p13) or t(5;12)(q31;p13).	21

Citation

Dessen P

GSX2 (GS homeobox 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46301