Identity
HGNC
LOCATION
14q23.1
LOCUSID
ALIAS
DAPPER,DAPPER1,DPR1,FRODO,HDPR1,TBS2,THYEX3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51339
MIM: 607861
HGNC: 17748
Ensembl: ENSG00000165617
Variants:
dbSNP: 51339
ClinVar: 51339
TCGA: ENSG00000165617
COSMIC: DACT1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37610179 | 2024 | Different expression of DACT1, DACT2, and CYCLIN D1 genes in human colorectal cancer tissues and its association with clinicopathological characteristics. | 0 |
| 37610179 | 2024 | Different expression of DACT1, DACT2, and CYCLIN D1 genes in human colorectal cancer tissues and its association with clinicopathological characteristics. | 0 |
| 36066768 | 2023 | Heterozygous variants in the DVL2 interaction region of DACT1 cause CAKUT and features of Townes-Brocks syndrome 2. | 2 |
| 36066768 | 2023 | Heterozygous variants in the DVL2 interaction region of DACT1 cause CAKUT and features of Townes-Brocks syndrome 2. | 2 |
| 35121825 | 2022 | M(6)A demethylase FTO-mediated downregulation of DACT1 mRNA stability promotes Wnt signaling to facilitate osteosarcoma progression. | 20 |
| 35510412 | 2022 | Disheveled binding antagonist of β-catenin 1 interacted with β-catenin and connexin 43 in human-induced pluripotent stem cells-derived cardiomyocytes. | 1 |
| 35121825 | 2022 | M(6)A demethylase FTO-mediated downregulation of DACT1 mRNA stability promotes Wnt signaling to facilitate osteosarcoma progression. | 20 |
| 35510412 | 2022 | Disheveled binding antagonist of β-catenin 1 interacted with β-catenin and connexin 43 in human-induced pluripotent stem cells-derived cardiomyocytes. | 1 |
| 33843483 | 2021 | DACT1 variants and colorectal cancer. | 0 |
| 34350095 | 2021 | Histone Deacetylation Regulated by KDM1A to Suppress DACT1 in Proliferation and Migration of Cervical Cancer. | 1 |
| 33843483 | 2021 | DACT1 variants and colorectal cancer. | 0 |
| 34350095 | 2021 | Histone Deacetylation Regulated by KDM1A to Suppress DACT1 in Proliferation and Migration of Cervical Cancer. | 1 |
| 31978940 | 2020 | Cyclin G2 regulates canonical Wnt signalling via interaction with Dapper1 to attenuate tubulointerstitial fibrosis in diabetic nephropathy. | 7 |
| 31978940 | 2020 | Cyclin G2 regulates canonical Wnt signalling via interaction with Dapper1 to attenuate tubulointerstitial fibrosis in diabetic nephropathy. | 7 |
| 30547803 | 2018 | Cyclin G2 suppresses Wnt/β-catenin signaling and inhibits gastric cancer cell growth and migration through Dapper1. | 27 |
Citation
Dessen P
DACT1 (dishevelled binding antagonist of beta catenin 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46315/dact1
