C1D (C1D nuclear receptor corepressor)

2007-02-01  

Identity

HGNC
LOCATION
2p14
LOCUSID
ALIAS
LRP1,Rrp47,SUN-CoR,SUNCOR,hC1D
FUSION GENES

Other Information

Locus ID:

NCBI: 10438
MIM: 606997
HGNC: 29911
Ensembl: ENSG00000197223

Variants:

dbSNP: 10438
ClinVar: 10438
TCGA: ENSG00000197223
COSMIC: C1D

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197223ENST00000355848Q13901
ENSG00000197223ENST00000407324J3KPZ4
ENSG00000197223ENST00000409302Q13901
ENSG00000197223ENST00000410067Q13901

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
RNA degradationKEGGko03018
RNA degradationKEGGhsa03018
Gene ExpressionREACTOMER-HSA-74160
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
301656702018C1D is not directly involved in the repair of UV-damaged DNA but protects cells from oxidative stress by regulating gene expressions in human cell lines.2
301656702018C1D is not directly involved in the repair of UV-damaged DNA but protects cells from oxidative stress by regulating gene expressions in human cell lines.2
204069642010Risk of meningioma and common variation in genes related to innate immunity.21
204387852010Polymorphisms in innate immunity genes and risk of childhood leukemia.12
205305792010XPB induces C1D expression to counteract UV-induced apoptosis.6
204069642010Risk of meningioma and common variation in genes related to innate immunity.21
204387852010Polymorphisms in innate immunity genes and risk of childhood leukemia.12
205305792010XPB induces C1D expression to counteract UV-induced apoptosis.6
194235402009Common variation in genes related to innate immunity and risk of adult glioma.35
194235402009Common variation in genes related to innate immunity and risk of adult glioma.35
174127072007C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processing.74
175997752007C1D is a major autoantibody target in patients with the polymyositis-scleroderma overlap syndrome.5
174127072007C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processing.74
175997752007C1D is a major autoantibody target in patients with the polymyositis-scleroderma overlap syndrome.5
118017382002DNA damage-dependent interaction of the nuclear matrix protein C1D with Translin-associated factor X (TRAX).17

Citation

Dessen P

C1D (C1D nuclear receptor corepressor)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46324/c1d