COIL (coilin)

2007-02-01  

Identity

HGNC
COIL
LOCATION
17q22
LOCUSID
8161
ALIAS
CLN80,p80-coilin
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8161
MIM: 600272
HGNC: 2184
Ensembl: ENSG00000121058

Variants:

dbSNP: 8161
ClinVar: 8161
TCGA: ENSG00000121058
COSMIC: COIL

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000121058ENST00000240316P38432
ENSG00000121058ENST00000573008I3L369

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
377959842023The Cajal body protein p80-coilin forms a complex with the adenovirus L4-22K protein and facilitates the nuclear export of adenovirus mRNA.1
377959842023The Cajal body protein p80-coilin forms a complex with the adenovirus L4-22K protein and facilitates the nuclear export of adenovirus mRNA.1
343197632021Coilin enhances phosphorylation and stability of DGCR8 and promotes miRNA biogenesis.3
343197632021Coilin enhances phosphorylation and stability of DGCR8 and promotes miRNA biogenesis.3
327644152020The Impact of Coilin Nonsynonymous SNP Variants E121K and V145I on Cell Growth and Cajal Body Formation: The First Characterization.3
327644152020The Impact of Coilin Nonsynonymous SNP Variants E121K and V145I on Cell Growth and Cajal Body Formation: The First Characterization.3
253477362015Nuclear accumulation of annexin A2 contributes to chromosomal instability by coilin-mediated centromere damage.6
254773782015Human cells lacking coilin and Cajal bodies are proficient in telomerase assembly, trafficking and telomere maintenance.29
259701352015Coilin: The first 25 years.38
260683042015VRK1 regulates Cajal body dynamics and protects coilin from proteasomal degradation in cell cycle.20
253477362015Nuclear accumulation of annexin A2 contributes to chromosomal instability by coilin-mediated centromere damage.6
254773782015Human cells lacking coilin and Cajal bodies are proficient in telomerase assembly, trafficking and telomere maintenance.29
259701352015Coilin: The first 25 years.38
260683042015VRK1 regulates Cajal body dynamics and protects coilin from proteasomal degradation in cell cycle.20
244131652014The SMN Tudor SIM-like domain is key to SmD1 and coilin interactions and to Cajal body biogenesis.13

Citation

Dessen P

COIL (coilin)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46332