CALD1 (caldesmon 1)

2007-02-01  

Identity

HGNC
CALD1
LOCATION
7q33
LOCUSID
800
ALIAS
CDM,H-CAD,HCAD,L-CAD,LCAD,NAG22
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 800
MIM: 114213
HGNC: 1441
Ensembl: ENSG00000122786

Variants:

dbSNP: 800
ClinVar: 800
TCGA: ENSG00000122786
COSMIC: CALD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000122786ENST00000361675Q05682
ENSG00000122786ENST00000361901Q05682
ENSG00000122786ENST00000361901A0A140VKA0
ENSG00000122786ENST00000393118Q05682
ENSG00000122786ENST00000417172Q05682
ENSG00000122786ENST00000417172A0A140VKA0
ENSG00000122786ENST00000422748Q05682
ENSG00000122786ENST00000424922Q05682
ENSG00000122786ENST00000430085F8WE61
ENSG00000122786ENST00000435928C9JE79
ENSG00000122786ENST00000436461C9J813
ENSG00000122786ENST00000443197E9PGZ1
ENSG00000122786ENST00000445569C9JEK3
ENSG00000122786ENST00000454108C9JE79
ENSG00000122786ENST00000495522E7EX44

Expression (GTEx)

0
500
1000
1500
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Vascular smooth muscle contractionKEGGhsa04270
Vascular smooth muscle contractionKEGGko04270
Muscle contractionREACTOMER-HSA-397014
Smooth Muscle ContractionREACTOMER-HSA-445355

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
383656112024Upregulation of CALD1 predicted a poor prognosis for platinum-treated ovarian cancer and revealed it as a potential therapeutic resistance target.0
383704082024The gene expression of CALD1, CDH2, and POSTN in fibroblast are related to idiopathic pulmonary fibrosis.0
383656112024Upregulation of CALD1 predicted a poor prognosis for platinum-treated ovarian cancer and revealed it as a potential therapeutic resistance target.0
383704082024The gene expression of CALD1, CDH2, and POSTN in fibroblast are related to idiopathic pulmonary fibrosis.0
370176802023METTL14 Promotes Oral Squamous Cell Carcinoma Progression by Regulating the mRNA and m6A Levels of CALD1.1
370176802023METTL14 Promotes Oral Squamous Cell Carcinoma Progression by Regulating the mRNA and m6A Levels of CALD1.1
282559762017Association of rs 3807337 polymorphism of CALD1 gene with diabetic nephropathy occurrence in type 1 diabetes - preliminary results of a family-based study.2
292354902017Fibroblasts play a potential role in bone destruction via osteopontin related caldesmon expression and polymerization in human non-functioning pituitary adenomas.4
282559762017Association of rs 3807337 polymorphism of CALD1 gene with diabetic nephropathy occurrence in type 1 diabetes - preliminary results of a family-based study.2
292354902017Fibroblasts play a potential role in bone destruction via osteopontin related caldesmon expression and polymerization in human non-functioning pituitary adenomas.4
266572942016Annexin-A1 and caldesmon are associated with resistance to tamoxifen in estrogen receptor positive recurrent breast cancer.17
266572942016Annexin-A1 and caldesmon are associated with resistance to tamoxifen in estrogen receptor positive recurrent breast cancer.17
264309612015Overexpression of caldesmon is associated with tumor progression in patients with primary non-muscle-invasive bladder cancer.16
264309612015Overexpression of caldesmon is associated with tumor progression in patients with primary non-muscle-invasive bladder cancer.16
245513052014Smoothelin and caldesmon are reliable markers for distinguishing muscularis propria from desmoplasia: a critical distinction for accurate staging colorectal adenocarcinoma.1

Citation

Dessen P

CALD1 (caldesmon 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46343