Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9817
MIM: 606016
HGNC: 23177
Ensembl: ENSG00000079999
Variants:
dbSNP: 9817
ClinVar: 9817
TCGA: ENSG00000079999
COSMIC: KEAP1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38159594 | 2024 | The role of Keap1-Nrf2 signaling pathway during the progress and therapy of diabetic retinopathy. | 1 |
| 38170368 | 2024 | Study of the effect of keap1 on oxidative stress in human umbilical cord mesenchymal stem cells. | 0 |
| 38383479 | 2024 | A tumor suppressor protein encoded by circKEAP1 inhibits osteosarcoma cell stemness and metastasis by promoting vimentin proteasome degradation and activating anti-tumor immunity. | 1 |
| 38479222 | 2024 | GSTP alleviates acute lung injury by S-glutathionylation of KEAP1 and subsequent activation of NRF2 pathway. | 0 |
| 38556546 | 2024 | Ceramide kinase-mediated C1P metabolism attenuates acute liver injury by inhibiting the interaction between KEAP1 and NRF2. | 1 |
| 38159594 | 2024 | The role of Keap1-Nrf2 signaling pathway during the progress and therapy of diabetic retinopathy. | 1 |
| 38170368 | 2024 | Study of the effect of keap1 on oxidative stress in human umbilical cord mesenchymal stem cells. | 0 |
| 38383479 | 2024 | A tumor suppressor protein encoded by circKEAP1 inhibits osteosarcoma cell stemness and metastasis by promoting vimentin proteasome degradation and activating anti-tumor immunity. | 1 |
| 38479222 | 2024 | GSTP alleviates acute lung injury by S-glutathionylation of KEAP1 and subsequent activation of NRF2 pathway. | 0 |
| 38556546 | 2024 | Ceramide kinase-mediated C1P metabolism attenuates acute liver injury by inhibiting the interaction between KEAP1 and NRF2. | 1 |
| 36730618 | 2023 | FXR1 facilitates axitinib resistance in clear cell renal cell carcinoma via regulating KEAP1/Nrf2 signaling pathway. | 3 |
| 36913799 | 2023 | miR-125b-5p in adipose derived stem cells exosome alleviates pulmonary microvascular endothelial cells ferroptosis via Keap1/Nrf2/GPX4 in sepsis lung injury. | 37 |
| 36930785 | 2023 | The KEAP1-NRF2 System and Neurodegenerative Diseases. | 11 |
| 36965071 | 2023 | DDRGK1 Enhances Osteosarcoma Chemoresistance via Inhibiting KEAP1-Mediated NRF2 Ubiquitination. | 7 |
| 37146513 | 2023 | The KEAP1-NRF2 pathway: Targets for therapy and role in cancer. | 32 |
Citation
Dessen P
KEAP1 (kelch like ECH associated protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46354/keap1
