CCL18 (C-C motif chemokine ligand 18)

2007-02-01  

Identity

HGNC
CCL18
LOCATION
17q12
LOCUSID
6362
ALIAS
AMAC-1,AMAC1,CKb7,DC-CK1,DCCK1,MIP-4,PARC,SCYA18

Other Information

Locus ID:

NCBI: 6362
MIM: 603757
HGNC: 10616
Ensembl: ENSG00000275385

Variants:

dbSNP: 6362
ClinVar: 6362
TCGA: ENSG00000275385
COSMIC: CCL18

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000275385ENST00000616054P55774

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Cytokine-cytokine receptor interactionKEGGhsa04060
Chemokine signaling pathwayKEGGko04062
Chemokine signaling pathwayKEGGhsa04062

References

Pubmed IDYearTitleCitations
383346302024Pro-Fibrotic Effects of CCL18 on Human Lung Fibroblasts Are Mediated via CCR6.1
383346302024Pro-Fibrotic Effects of CCL18 on Human Lung Fibroblasts Are Mediated via CCR6.1
364552322023CCL18 promotes migration and invasion of multiple myeloma cells and is associated with poor prognosis.3
369670812023Identification and validation of a CCL18-related signature for prediction of overall survival in patients with uveal melanoma.0
370462422023Adipose tissue specific CCL18 associates with cardiometabolic diseases in non-obese individuals implicating CD4(+) T cells.1
364552322023CCL18 promotes migration and invasion of multiple myeloma cells and is associated with poor prognosis.3
369670812023Identification and validation of a CCL18-related signature for prediction of overall survival in patients with uveal melanoma.0
370462422023Adipose tissue specific CCL18 associates with cardiometabolic diseases in non-obese individuals implicating CD4(+) T cells.1
332876052022Is CCL18 a potential biomarker of type-2 asthma endotypes?0
350415142022Chemokine CCL18 Promotes Phagocytosis Through Its Receptor CCR8 Rather than PITPNM3 in Human Microglial Cells.0
356668122022IL6 and CCL18 Mediate Cross-talk between VHL-Deficient Kidney Cells and Macrophages during Development of Renal Cell Carcinoma.6
359556702022CCL18 Expression Is Higher in a Glioblastoma Multiforme Tumor than in the Peritumoral Area and Causes the Migration of Tumor Cells Sensitized by Hypoxia.2
332876052022Is CCL18 a potential biomarker of type-2 asthma endotypes?0
350415142022Chemokine CCL18 Promotes Phagocytosis Through Its Receptor CCR8 Rather than PITPNM3 in Human Microglial Cells.0
356668122022IL6 and CCL18 Mediate Cross-talk between VHL-Deficient Kidney Cells and Macrophages during Development of Renal Cell Carcinoma.6

Citation

Dessen P

CCL18 (C-C motif chemokine ligand 18)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46358/js/lib/haematological-explorer/tumors-explorer/