P2RX5 (purinergic receptor P2X 5)

2007-02-01  

Identity

HGNC
LOCATION
17p13.2
LOCUSID
ALIAS
LRH-1,P2X5,P2X5R
FUSION GENES

Other Information

Locus ID:

NCBI: 5026
MIM: 602836
HGNC: 8536
Ensembl: ENSG00000083454

Variants:

dbSNP: 5026
ClinVar: 5026
TCGA: ENSG00000083454
COSMIC: P2RX5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000083454ENST00000225328Q93086
ENSG00000083454ENST00000345901Q93086
ENSG00000083454ENST00000547178Q93086
ENSG00000083454ENST00000551178Q93086
ENSG00000083454ENST00000552050B4DEG2
ENSG00000083454ENST00000552276K7EQ78
ENSG00000083454ENST00000552456H0YHT9
ENSG00000083454ENST00000552723H0YII8

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Calcium signaling pathwayKEGGko04020
Neuroactive ligand-receptor interactionKEGGko04080
Calcium signaling pathwayKEGGhsa04020
Neuroactive ligand-receptor interactionKEGGhsa04080
HemostasisREACTOMER-HSA-109582
Platelet homeostasisREACTOMER-HSA-418346
Platelet calcium homeostasisREACTOMER-HSA-418360
Elevation of cytosolic Ca2+ levelsREACTOMER-HSA-139853

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
248685472014Correlation between urothelial differentiation and sensory proteins P2X3, P2X5, TRPV1, and TRPV4 in normal urothelium and papillary carcinoma of human bladder.14
250804782014ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes.99
251810382014A truncation variant of the cation channel P2RX5 is upregulated during T cell activation.7
248685472014Correlation between urothelial differentiation and sensory proteins P2X3, P2X5, TRPV1, and TRPV4 in normal urothelium and papillary carcinoma of human bladder.14
250804782014ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes.99
251810382014A truncation variant of the cation channel P2RX5 is upregulated during T cell activation.7
202238792010Genetic and functional analysis of human P2X5 reveals a distinct pattern of exon 10 polymorphism with predominant expression of the nonfunctional receptor isoform.17
210928622010Sensing muscle ischemia: coincident detection of acid and ATP via interplay of two ion channels.91
202238792010Genetic and functional analysis of human P2X5 reveals a distinct pattern of exon 10 polymorphism with predominant expression of the nonfunctional receptor isoform.17
210928622010Sensing muscle ischemia: coincident detection of acid and ATP via interplay of two ion channels.91
187199142009Aberrant expression of the hematopoietic-restricted minor histocompatibility antigen LRH-1 on solid tumors results in efficient cytotoxic T cell-mediated lysis.7
190747342009Myeloid leukemic progenitor cells can be specifically targeted by minor histocompatibility antigen LRH-1-reactive cytotoxic T cells.16
187199142009Aberrant expression of the hematopoietic-restricted minor histocompatibility antigen LRH-1 on solid tumors results in efficient cytotoxic T cell-mediated lysis.7
190747342009Myeloid leukemic progenitor cells can be specifically targeted by minor histocompatibility antigen LRH-1-reactive cytotoxic T cells.16
169673062006Purinoceptor expression on keratinocytes reflects their function on the epidermis during chronic venous insufficiency.1

Citation

Dessen P

P2RX5 (purinergic receptor P2X 5)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46407/p2rx5