Identity
HGNC
LOCATION
17q21.2
LOCUSID
ALIAS
BLR2,CC-CKR-7,CCR-7,CD197,CDw197,CMKBR7,EBI1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1236
MIM: 600242
HGNC: 1608
Ensembl: ENSG00000126353
Variants:
dbSNP: 1236
ClinVar: 1236
TCGA: ENSG00000126353
COSMIC: CCR7
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000126353 | ENST00000246657 | P32248 |
| ENSG00000126353 | ENST00000246657 | A0N0Q0 |
| ENSG00000126353 | ENST00000578085 | J3KTN5 |
| ENSG00000126353 | ENST00000579344 | J3KSS9 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36675182 | 2023 | Heparin Specifically Interacts with Basic BBXB Motifs of the Chemokine CCL21 to Define CCR7 Signaling. | 2 |
| 37030121 | 2023 | Effects of chemokine receptor CCR7 in the pathophysiology and clinical features of the immuno-inflammatory response in primary pterygium. | 0 |
| 37208608 | 2023 | CCL19/CCR7 drives regulatory T cell migration and indicates poor prognosis in gastric cancer. | 2 |
| 37314567 | 2023 | CCL21-CCR7 signaling promotes microglia/macrophage recruitment and chemotherapy resistance in glioblastoma. | 1 |
| 36675182 | 2023 | Heparin Specifically Interacts with Basic BBXB Motifs of the Chemokine CCL21 to Define CCR7 Signaling. | 2 |
| 37030121 | 2023 | Effects of chemokine receptor CCR7 in the pathophysiology and clinical features of the immuno-inflammatory response in primary pterygium. | 0 |
| 37208608 | 2023 | CCL19/CCR7 drives regulatory T cell migration and indicates poor prognosis in gastric cancer. | 2 |
| 37314567 | 2023 | CCL21-CCR7 signaling promotes microglia/macrophage recruitment and chemotherapy resistance in glioblastoma. | 1 |
| 35108538 | 2022 | Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics. | 7 |
| 35133060 | 2022 | CXCL12 promotes CCR7 ligand-mediated breast cancer cell invasion and migration toward lymphatic vessels. | 12 |
| 35203305 | 2022 | C-C Chemokine Receptor 7 in Cancer. | 13 |
| 35278713 | 2022 | Lack of DOCK8 impairs the primary biologic functions of human NK cells and abrogates CCR7 surface expression in a WASP-independent manner. | 1 |
| 35333927 | 2022 | WGCNA and molecular docking reveal key hub genes and potential natural inhibitor in interstitial cystitis/bladder pain syndrome. | 1 |
| 35400595 | 2022 | CCR7 expression in CD19 chimeric antigen receptor-engineered natural killer cells improves migration toward CCL19-expressing lymphoma cells and increases tumor control in mice with human lymphoma. | 9 |
| 35422889 | 2022 | lncRNA DARS-AS1 Promoted Osteosarcoma Progression through Regulating miR-532-3p/CCR7. | 5 |
Citation
Dessen P
CCR7 (C-C motif chemokine receptor 7)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46422/ccr7
