Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5493
MIM: 602871
HGNC: 9273
Ensembl: ENSG00000118898
Variants:
dbSNP: 5493
ClinVar: 5493
TCGA: ENSG00000118898
COSMIC: PPL
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000118898 | ENST00000345988 | O60437 |
| ENSG00000118898 | ENST00000590782 | K7EKI8 |
| ENSG00000118898 | ENST00000592772 | K7EQ71 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34815391 | 2021 | Desmoplakin and periplakin genetically and functionally contribute to eosinophilic esophagitis. | 14 |
| 34815391 | 2021 | Desmoplakin and periplakin genetically and functionally contribute to eosinophilic esophagitis. | 14 |
| 32081916 | 2020 | Binding of the periplakin linker requires vimentin acidic residues D176 and E187. | 3 |
| 32081916 | 2020 | Binding of the periplakin linker requires vimentin acidic residues D176 and E187. | 3 |
| 30516430 | 2019 | SUMOylation of periplakin is critical for efficient reorganization of keratin filament network. | 6 |
| 30787334 | 2019 | The 4717C > G polymorphism in periplakin modulates sensitivity to EGFR inhibitors. | 2 |
| 30516430 | 2019 | SUMOylation of periplakin is critical for efficient reorganization of keratin filament network. | 6 |
| 30787334 | 2019 | The 4717C > G polymorphism in periplakin modulates sensitivity to EGFR inhibitors. | 2 |
| 28068625 | 2017 | Loss of periplakin expression is associated with the tumorigenesis of colorectal carcinoma. | 15 |
| 28068625 | 2017 | Loss of periplakin expression is associated with the tumorigenesis of colorectal carcinoma. | 15 |
| 27717390 | 2016 | Perip7lakin is a target for autoimmunity in asthma. | 8 |
| 27717390 | 2016 | Perip7lakin is a target for autoimmunity in asthma. | 8 |
| 25637025 | 2015 | Activation of human γδ T cells by cytosolic interactions of BTN3A1 with soluble phosphoantigens and the cytoskeletal adaptor periplakin. | 85 |
| 25637025 | 2015 | Activation of human γδ T cells by cytosolic interactions of BTN3A1 with soluble phosphoantigens and the cytoskeletal adaptor periplakin. | 85 |
| 24942859 | 2014 | Loss of periplakin expression is associated with pathological stage and cancer-specific survival in patients with urothelial carcinoma of the urinary bladder. | 13 |
Citation
Dessen P
PPL (periplakin)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46425/ppl
