Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1382
MIM: 180231
HGNC: 2339
Ensembl: ENSG00000143320
Variants:
dbSNP: 1382
ClinVar: 1382
TCGA: ENSG00000143320
COSMIC: CRABP2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000143320 | ENST00000368220 | Q5SYZ4 |
| ENSG00000143320 | ENST00000368221 | P29373 |
| ENSG00000143320 | ENST00000368222 | P29373 |
| ENSG00000143320 | ENST00000621784 | P29373 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by Retinoic Acid | REACTOME | R-HSA-5362517 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38195606 | 2024 | CRABP2 affects chemotherapy resistance of ovarian cancer by regulating the expression of HIF1α. | 1 |
| 38195606 | 2024 | CRABP2 affects chemotherapy resistance of ovarian cancer by regulating the expression of HIF1α. | 1 |
| 36736488 | 2023 | The prognostic gene CRABP2 affects drug sensitivity by regulating docetaxel-induced apoptosis in breast invasive carcinoma: A pan-cancer analysis. | 5 |
| 37715025 | 2023 | The heterogeneity of tumour immune microenvironment revealing the CRABP2/CD69 signature discriminates distinct clinical outcomes in breast cancer. | 3 |
| 38186580 | 2023 | CRABP2 regulates infiltration of cancer-associated fibroblasts and immune response in melanoma. | 1 |
| 36736488 | 2023 | The prognostic gene CRABP2 affects drug sensitivity by regulating docetaxel-induced apoptosis in breast invasive carcinoma: A pan-cancer analysis. | 5 |
| 37715025 | 2023 | The heterogeneity of tumour immune microenvironment revealing the CRABP2/CD69 signature discriminates distinct clinical outcomes in breast cancer. | 3 |
| 38186580 | 2023 | CRABP2 regulates infiltration of cancer-associated fibroblasts and immune response in melanoma. | 1 |
| 35260193 | 2022 | Targeting CRABP-II overcomes pancreatic cancer drug resistance by reversing lipid raft cholesterol accumulation and AKT survival signaling. | 9 |
| 35396749 | 2022 | Circular RNA hsa_circ_0011298 enhances Taxol resistance of non-small cell lung cancer by regulating miR-486-3p/CRABP2 axis. | 6 |
| 35442568 | 2022 | CRABP2 accelerates epithelial mesenchymal transition in serous ovarian cancer cells by promoting TRIM16 methylation via upregulating EZH2 expression. | 7 |
| 36163055 | 2022 | CRABP2 - A novel biomarker for high-risk endometrial cancer. | 2 |
| 36195596 | 2022 | Upregulation of CRABP2 by TET1-mediated DNA hydroxymethylation attenuates mitochondrial apoptosis and promotes oxaliplatin resistance in gastric cancer. | 11 |
| 36240291 | 2022 | CRABP2 Is Associated With Thyroid Cancer Recurrence and Promotes Invasion via the Integrin/FAK/AKT Pathway. | 11 |
| 35260193 | 2022 | Targeting CRABP-II overcomes pancreatic cancer drug resistance by reversing lipid raft cholesterol accumulation and AKT survival signaling. | 9 |
Citation
Dessen P
CRABP2 (cellular retinoic acid binding protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46427/crabp2
