CD209 (CD209 molecule)

2007-02-01  

Identity

HGNC
LOCATION
19p13.2
LOCUSID
ALIAS
CDSIGN,CLEC4L,DC-SIGN,DC-SIGN1,hDC-SIGN

Other Information

Locus ID:

NCBI: 30835
MIM: 604672
HGNC: 1641
Ensembl: ENSG00000090659

Variants:

dbSNP: 30835
ClinVar: 30835
TCGA: ENSG00000090659
COSMIC: CD209

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000090659ENST00000204801Q9NNX6
ENSG00000090659ENST00000315591Q9NNX6
ENSG00000090659ENST00000315599Q9NNX6
ENSG00000090659ENST00000354397Q9NNX6
ENSG00000090659ENST00000394161Q9NNX6
ENSG00000090659ENST00000394173X6RB12
ENSG00000090659ENST00000593660M0QZG5
ENSG00000090659ENST00000593821M0R0P0
ENSG00000090659ENST00000601256Q9NNX6
ENSG00000090659ENST00000601951Q9NNX6
ENSG00000090659ENST00000602261Q9NNX6

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
PhagosomeKEGGko04145
PhagosomeKEGGhsa04145
MeaslesKEGGko05162
MeaslesKEGGhsa05162
TuberculosisKEGGko05152
TuberculosisKEGGhsa05152
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Innate Immune SystemREACTOMER-HSA-168249
C-type lectin receptors (CLRs)REACTOMER-HSA-5621481
CD209 (DC-SIGN) signalingREACTOMER-HSA-5621575
Butyrophilin (BTN) family interactionsREACTOMER-HSA-8851680

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
365041052023DC-SIGN and Galectin-3 individually and collaboratively regulate H5N1 and H7N9 avian influenza A virus infection via interaction with viral envelope hemagglutinin protein.0
378440992023SARS-CoV-2 suppresses TLR4-induced immunity by dendritic cells via C-type lectin receptor DC-SIGN.3
365041052023DC-SIGN and Galectin-3 individually and collaboratively regulate H5N1 and H7N9 avian influenza A virus infection via interaction with viral envelope hemagglutinin protein.0
378440992023SARS-CoV-2 suppresses TLR4-induced immunity by dendritic cells via C-type lectin receptor DC-SIGN.3
345300822022Association of single nucleotide polymorphisms in the CD209, MMP9, TNFA and IFNG genes with susceptibility to Japanese encephalitis in children from North India.3
357037152022Association of CD209 (DC-SIGN) rs735240 SNV with paucibacillary leprosy in the Brazilian population and its functional effects.0
357907692022Genetic polymorphisms in TLR3, IL10 and CD209 influence the risk of BK polyomavirus infection after kidney transplantation.4
363567942022Importance of NFκβ, IL-10 serum levels and DC-SIGN polymorphic haplotypes in determining dengue disease severity among eastern Indian patients.0
345300822022Association of single nucleotide polymorphisms in the CD209, MMP9, TNFA and IFNG genes with susceptibility to Japanese encephalitis in children from North India.3
357037152022Association of CD209 (DC-SIGN) rs735240 SNV with paucibacillary leprosy in the Brazilian population and its functional effects.0
357907692022Genetic polymorphisms in TLR3, IL10 and CD209 influence the risk of BK polyomavirus infection after kidney transplantation.4
363567942022Importance of NFκβ, IL-10 serum levels and DC-SIGN polymorphic haplotypes in determining dengue disease severity among eastern Indian patients.0
330906002021Synthesis of Asparagine Derivatives Harboring a Lewis X Type DC-SIGN Ligand and Evaluation of their Impact on Immunomodulation in Multiple Sclerosis.3
335352352021Association of Genetic Polymorphisms in DC-SIGN, Toll-Like Receptor 3, and Tumor Necrosis Factor α Genes and the Lewis-Negative Phenotype With Chikungunya Infection and Disease in Nicaragua.9
335903432021Polymorphisms in the DC-SIGN gene and their association with the severity of hand, foot, and mouth disease caused by enterovirus 71.2

Citation

Dessen P

CD209 (CD209 molecule)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46435/cd209