MAPK8IP1 (mitogen-activated protein kinase 8 interacting protein 1)

2007-02-01  

Identity

HGNC
MAPK8IP1
LOCATION
11p11.2
LOCUSID
9479
ALIAS
IB1,JIP-1,JIP1,PRKM8IP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9479
MIM: 604641
HGNC: 6882
Ensembl: ENSG00000121653

Variants:

dbSNP: 9479
ClinVar: 9479
TCGA: ENSG00000121653
COSMIC: MAPK8IP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000121653ENST00000241014Q9UQF2
ENSG00000121653ENST00000395629E9PBB9

Expression (GTEx)

0
50
100
150
200
250
300
350
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MAPK signaling pathwayKEGGko04010
MAPK signaling pathwayKEGGhsa04010

References

Pubmed IDYearTitleCitations
369024222023Dual Role of Mitogen-Activated Protein Kinase 8 Interacting Protein-1 in Inflammasome and Pancreatic β-Cell Function.2
369024222023Dual Role of Mitogen-Activated Protein Kinase 8 Interacting Protein-1 in Inflammasome and Pancreatic β-Cell Function.2
350928152022Identification of Key Biomarkers and Immune Infiltration in Sporadic Vestibular Schwannoma Basing Transcriptome-Wide Profiling.4
350928152022Identification of Key Biomarkers and Immune Infiltration in Sporadic Vestibular Schwannoma Basing Transcriptome-Wide Profiling.4
338486452021Retrospective analysis of the incidence and predictive factors of parametrial involvement in FIGO IB1 cervical cancer.3
340142612021Sequential dynein effectors regulate axonal autophagosome motility in a maturation-dependent pathway.47
338486452021Retrospective analysis of the incidence and predictive factors of parametrial involvement in FIGO IB1 cervical cancer.3
340142612021Sequential dynein effectors regulate axonal autophagosome motility in a maturation-dependent pathway.47
300262352018Characterization of the binding mode of JNK-interacting protein 1 (JIP1) to kinesin-light chain 1 (KLC1).3
300262352018Characterization of the binding mode of JNK-interacting protein 1 (JIP1) to kinesin-light chain 1 (KLC1).3
278916692017A molecular dynamics study of the binary complexes of APP, JIP1, and the cargo binding domain of KLC.2
278916692017A molecular dynamics study of the binary complexes of APP, JIP1, and the cargo binding domain of KLC.2
231722262013Lysine 63-linked ubiquitination modulates mixed lineage kinase-3 interaction with JIP1 scaffold protein in cytokine-induced pancreatic β cell death.11
233609212013Survival is associated with genetic variation in inflammatory pathway genes among patients with resected and unresected pancreatic cancer.7
237706732013The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complex.13

Citation

Dessen P

MAPK8IP1 (mitogen-activated protein kinase 8 interacting protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46440/tumors-explorer/gene-fusions-explorer/gene-fusions-explorer/