Identity
HGNC
LOCATION
14q23.3
LOCUSID
ALIAS
EIF-2,EIF-2A,EIF-2alpha,EIF2,EIF2A
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1965
MIM: 603907
HGNC: 3265
Ensembl: ENSG00000134001
Variants:
dbSNP: 1965
ClinVar: 1965
TCGA: ENSG00000134001
COSMIC: EIF2S1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38151653 | 2024 | MiR-3074-5p Regulates Trophoblasts Function via EIF2S1/GDF15 Pathway in Recurrent Miscarriage. | 0 |
| 38272235 | 2024 | CHIP suppresses the proliferation and migration of A549 cells by mediating the ubiquitination of eIF2α and upregulation of tumor suppressor RBM5. | 0 |
| 38151653 | 2024 | MiR-3074-5p Regulates Trophoblasts Function via EIF2S1/GDF15 Pathway in Recurrent Miscarriage. | 0 |
| 38272235 | 2024 | CHIP suppresses the proliferation and migration of A549 cells by mediating the ubiquitination of eIF2α and upregulation of tumor suppressor RBM5. | 0 |
| 37828427 | 2023 | Activation of BZW1 by CEBPB in macrophages promotes eIF2α phosphorylation-mediated metabolic reprogramming and endoplasmic reticulum stress in MRL/lpr lupus-prone mice. | 1 |
| 37828427 | 2023 | Activation of BZW1 by CEBPB in macrophages promotes eIF2α phosphorylation-mediated metabolic reprogramming and endoplasmic reticulum stress in MRL/lpr lupus-prone mice. | 1 |
| 34969763 | 2022 | Helicobacter pylori Targets in AGS Human Gastric Adenocarcinoma: In Situ Proteomic Profiling and Systematic Analysis. | 3 |
| 36438488 | 2022 | C9orf72 regulates the unfolded protein response and stress granule formation by interacting with eIF2α. | 5 |
| 34969763 | 2022 | Helicobacter pylori Targets in AGS Human Gastric Adenocarcinoma: In Situ Proteomic Profiling and Systematic Analysis. | 3 |
| 36438488 | 2022 | C9orf72 regulates the unfolded protein response and stress granule formation by interacting with eIF2α. | 5 |
| 33946018 | 2021 | Activation of the eIF2α/ATF4 axis drives triple-negative breast cancer radioresistance by promoting glutathione biosynthesis. | 25 |
| 34052329 | 2021 | PERK-eIF2α-ERK1/2 axis drives mesenchymal-endothelial transition of cancer-associated fibroblasts in pancreatic cancer. | 11 |
| 34625748 | 2021 | Higher-order phosphatase-substrate contacts terminate the integrated stress response. | 10 |
| 33946018 | 2021 | Activation of the eIF2α/ATF4 axis drives triple-negative breast cancer radioresistance by promoting glutathione biosynthesis. | 25 |
| 34052329 | 2021 | PERK-eIF2α-ERK1/2 axis drives mesenchymal-endothelial transition of cancer-associated fibroblasts in pancreatic cancer. | 11 |
Citation
Dessen P
EIF2S1 (eukaryotic translation initiation factor 2 subunit alpha)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46443/eif2s1
