Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 29941
MIM: 610714
HGNC: 17999
Ensembl: ENSG00000160447
Variants:
dbSNP: 29941
ClinVar: 29941
TCGA: ENSG00000160447
COSMIC: PKN3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000160447 | ENST00000291906 | Q6P5Z2 |
| ENSG00000160447 | ENST00000291906 | A0A024R8D6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33092266 | 2020 | A Screen for PKN3 Substrates Reveals an Activating Phosphorylation of ARHGAP18. | 2 |
| 33092266 | 2020 | A Screen for PKN3 Substrates Reveals an Activating Phosphorylation of ARHGAP18. | 2 |
| 30422386 | 2019 | The interaction of p130Cas with PKN3 promotes malignant growth. | 11 |
| 30422386 | 2019 | The interaction of p130Cas with PKN3 promotes malignant growth. | 11 |
| 26742562 | 2016 | PKN3 is the major regulator of angiogenesis and tumor metastasis in mice. | 17 |
| 26742562 | 2016 | PKN3 is the major regulator of angiogenesis and tumor metastasis in mice. | 17 |
| 27919031 | 2014 | Enzyme kinetics and distinct modulation of the protein kinase N family of kinases by lipid activators and small molecule inhibitors. | 15 |
| 27919031 | 2014 | Enzyme kinetics and distinct modulation of the protein kinase N family of kinases by lipid activators and small molecule inhibitors. | 15 |
| 22609186 | 2012 | Depletion of protein kinase N3 (PKN3) impairs actin and adherens junctions dynamics and attenuates endothelial cell activation. | 8 |
| 22609186 | 2012 | Depletion of protein kinase N3 (PKN3) impairs actin and adherens junctions dynamics and attenuates endothelial cell activation. | 8 |
| 21754995 | 2011 | Regulatory domain selectivity in the cell-type specific PKN-dependence of cell migration. | 42 |
| 21754995 | 2011 | Regulatory domain selectivity in the cell-type specific PKN-dependence of cell migration. | 42 |
| 15282551 | 2004 | PKN3 is required for malignant prostate cell growth downstream of activated PI 3-kinase. | 40 |
| 15282551 | 2004 | PKN3 is required for malignant prostate cell growth downstream of activated PI 3-kinase. | 40 |
Citation
Dessen P
PKN3 (protein kinase N3)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46487/pkn3
