MRPL41 (mitochondrial ribosomal protein L41)

2007-02-01  

Identity

HGNC
LOCATION
9q34.3
LOCUSID
ALIAS
BMRP,MRP-L27,MRPL27,PIG3,RPML27

Other Information

Locus ID:

NCBI: 64975
MIM: 611846
HGNC: 14492
Ensembl: ENSG00000182154

Variants:

dbSNP: 64975
ClinVar: 64975
TCGA: ENSG00000182154
COSMIC: MRPL41

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182154ENST00000371443Q8IXM3

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Mitochondrial translationREACTOMER-HSA-5368287
Mitochondrial translation initiationREACTOMER-HSA-5368286
Mitochondrial translation elongationREACTOMER-HSA-5389840
Mitochondrial translation terminationREACTOMER-HSA-5419276

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
241602662013Nuclear-encoded mitochondrial MTO1 and MRPL41 are regulated in an opposite epigenetic mode based on estrogen receptor status in breast cancer.8
241602662013Nuclear-encoded mitochondrial MTO1 and MRPL41 are regulated in an opposite epigenetic mode based on estrogen receptor status in breast cancer.8
227115032012Identification of a motif in BMRP required for interaction with Bcl-2 by site-directed mutagenesis studies.6
227115032012Identification of a motif in BMRP required for interaction with Bcl-2 by site-directed mutagenesis studies.6
212538512011Deletion mutational analysis of BMRP, a pro-apoptotic protein that binds to Bcl-2.3
212538512011Deletion mutational analysis of BMRP, a pro-apoptotic protein that binds to Bcl-2.3
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
155479502005BMRP is a Bcl-2 binding protein that induces apoptosis.15
160247962005Mitochondrial ribosomal protein L41 suppresses cell growth in association with p53 and p27Kip1.53
162569472005Mitochondrial ribosomal protein L41 mediates serum starvation-induced cell-cycle arrest through an increase of p21(WAF1/CIP1).21
155479502005BMRP is a Bcl-2 binding protein that induces apoptosis.15
160247962005Mitochondrial ribosomal protein L41 suppresses cell growth in association with p53 and p27Kip1.53
162569472005Mitochondrial ribosomal protein L41 mediates serum starvation-induced cell-cycle arrest through an increase of p21(WAF1/CIP1).21

Citation

Dessen P

MRPL41 (mitochondrial ribosomal protein L41)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46499/mrpl41