LEMD1 (LEM domain containing 1)

2007-02-01  

Identity

HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
CT50,LEMP-1
FUSION GENES

Other Information

Locus ID:

NCBI: 93273
MIM: 610480
HGNC: 18725
Ensembl: ENSG00000186007

Variants:

dbSNP: 93273
ClinVar: 93273
TCGA: ENSG00000186007
COSMIC: LEMD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000186007ENST00000367149Q68G75
ENSG00000186007ENST00000367151Q68G75
ENSG00000186007ENST00000367152Q68G75
ENSG00000186007ENST00000367153Q68G75
ENSG00000186007ENST00000367154Q68G75
ENSG00000186007ENST00000391936Q68G75
ENSG00000186007ENST00000495594Q68G75

Expression (GTEx)

0
50
100
150

References

Pubmed IDYearTitleCitations
369674592024Elevation of LEM Domain Containing 1 Predicts Poor Prognosis of NSCLC Patients and Triggers Malignant Stemness and Invasion of NSCLC Cells by Stimulating PI3K/AKT Pathway.0
369674592024Elevation of LEM Domain Containing 1 Predicts Poor Prognosis of NSCLC Patients and Triggers Malignant Stemness and Invasion of NSCLC Cells by Stimulating PI3K/AKT Pathway.0
352943192022LEM domain containing 1 (LEMD1) transcriptionally activated by SRY-related high-mobility-group box 4 (SOX4) accelerates the progression of colon cancer by upregulating phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway.3
359832492022Long Noncoding RNA LEMD1-AS1 Increases LEMD1 Expression and Activates PI3K-AKT Pathway to Promote Metastasis in Oral Squamous Cell Carcinoma.2
352943192022LEM domain containing 1 (LEMD1) transcriptionally activated by SRY-related high-mobility-group box 4 (SOX4) accelerates the progression of colon cancer by upregulating phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway.3
359832492022Long Noncoding RNA LEMD1-AS1 Increases LEMD1 Expression and Activates PI3K-AKT Pathway to Promote Metastasis in Oral Squamous Cell Carcinoma.2
346722372021Long non-coding RNA LINC00958 promotes colorectal cancer progression by enhancing the expression of LEM domain containing 1 via microRNA miR-3064-5p.4
346722372021Long non-coding RNA LINC00958 promotes colorectal cancer progression by enhancing the expression of LEM domain containing 1 via microRNA miR-3064-5p.4
310214502019LEM domain containing 1 promotes proliferation via activating the PI3K/Akt signaling pathway in gastric cancer.12
310214502019LEM domain containing 1 promotes proliferation via activating the PI3K/Akt signaling pathway in gastric cancer.12
282196432017Identification and functional analysis of variants of a cancer/testis antigen LEMD1 in colorectal cancer stem-like cells.14
282196432017Identification and functional analysis of variants of a cancer/testis antigen LEMD1 in colorectal cancer stem-like cells.14
272806332016LEM domain containing 1 promotes oral squamous cell carcinoma invasion and endothelial transmigration.15
272806332016LEM domain containing 1 promotes oral squamous cell carcinoma invasion and endothelial transmigration.15
206821772010Expression of two testis-specific genes, SPATA19 and LEMD1, in prostate cancer.25

Citation

Dessen P

LEMD1 (LEM domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46546/lemd1