TLR10 (toll like receptor 10)

2007-02-01 Affiliation

Identity

HGNC

TLR10

LOCATION

4p14

LOCUSID

81793

ALIAS

CD290

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 81793
MIM: 606270
HGNC: 15634
Ensembl: ENSG00000174123

Variants:

dbSNP: 81793
ClinVar: 81793
TCGA: ENSG00000174123
COSMIC: TLR10

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000174123	ENST00000308973	Q9BXR5
ENSG00000174123	ENST00000308973	A0A024R9W4
ENSG00000174123	ENST00000361424	Q9BXR5
ENSG00000174123	ENST00000361424	A0A024R9W4
ENSG00000174123	ENST00000502321	D6RHW6
ENSG00000174123	ENST00000506111	Q9BXR5
ENSG00000174123	ENST00000506111	A0A024R9W4
ENSG00000174123	ENST00000508334	Q9BXR5
ENSG00000174123	ENST00000508334	A0A024R9W4
ENSG00000174123	ENST00000613579	Q9BXR5
ENSG00000174123	ENST00000613579	A0A024R9W4
ENSG00000174123	ENST00000622002	Q9BXR5
ENSG00000174123	ENST00000622002	A0A024R9W4

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Disease	REACTOME	R-HSA-1643685
Diseases of Immune System	REACTOME	R-HSA-5260271
Diseases associated with the TLR signaling cascade	REACTOME	R-HSA-5602358
IRAK4 deficiency (TLR5)	REACTOME	R-HSA-5603037
Immune System	REACTOME	R-HSA-168256
Innate Immune System	REACTOME	R-HSA-168249
Toll-Like Receptors Cascades	REACTOME	R-HSA-168898
Toll Like Receptor 10 (TLR10) Cascade	REACTOME	R-HSA-168142
MyD88 cascade initiated on plasma membrane	REACTOME	R-HSA-975871
Toll Like Receptor 5 (TLR5) Cascade	REACTOME	R-HSA-168176

References

Pubmed ID	Year	Title	Citations
38296538	2024	Relationship of Toll-Like Receptor 7, 9, and 10 Polymorphisms and the Severity of Coronavirus Disease 2019.	0
38296538	2024	Relationship of Toll-Like Receptor 7, 9, and 10 Polymorphisms and the Severity of Coronavirus Disease 2019.	0
36934201	2023	Toll-like receptor 10 is down-regulated in serum of patients with relapsing-remitting multiple sclerosis but not associated with Epstein-Barr virus.	1
36934201	2023	Toll-like receptor 10 is down-regulated in serum of patients with relapsing-remitting multiple sclerosis but not associated with Epstein-Barr virus.	1
34595581	2022	TLR10 and Its Role in Immunity.	11
35122704	2022	Gene polymorphisms of TLR10: effects on bacterial meningitis outcomes in Angolan children.	1
35358679	2022	Toll-like receptor 10 expression in B cells is negatively correlated with the progression of primary Sjögren's disease.	2
35613551	2022	Regulation of TLR10 Expression and Its Role in Chemotaxis of Human Neutrophils.	2
35867184	2022	Toll-like receptor 10 has a role in human macrophage response against Streptococcus pneumoniae.	0
35994854	2022	TLR10 genotypes affect long-term graft function in tacrolimus-treated solid organ transplant recipients.	0
34595581	2022	TLR10 and Its Role in Immunity.	11
35122704	2022	Gene polymorphisms of TLR10: effects on bacterial meningitis outcomes in Angolan children.	1
35358679	2022	Toll-like receptor 10 expression in B cells is negatively correlated with the progression of primary Sjögren's disease.	2
35613551	2022	Regulation of TLR10 Expression and Its Role in Chemotaxis of Human Neutrophils.	2
35867184	2022	Toll-like receptor 10 has a role in human macrophage response against Streptococcus pneumoniae.	0

Citation

Dessen P

TLR10 (toll like receptor 10)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46568/img/teaching-explorer/meetings/