Identity
HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
ALR,ERV1,HERV1,HPO,HPO1,HPO2,HSS,MMCHD,MPMCD
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2671
MIM: 600924
HGNC: 4236
Ensembl: ENSG00000127554
Variants:
dbSNP: 2671
ClinVar: 2671
TCGA: ENSG00000127554
COSMIC: GFER
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000127554 | ENST00000248114 | P55789 |
| ENSG00000127554 | ENST00000561710 | H3BRD2 |
| ENSG00000127554 | ENST00000567719 | H3BQQ4 |
| ENSG00000127554 | ENST00000569451 | H3BRW3 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism of proteins | REACTOME | R-HSA-392499 |
| Mitochondrial protein import | REACTOME | R-HSA-1268020 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37666068 | 2023 | TMPRSS11D/ALR-mediated ER stress regulates the function of myeloid-derived suppressor cells in the cervical cancer microenvironment. | 1 |
| 37666068 | 2023 | TMPRSS11D/ALR-mediated ER stress regulates the function of myeloid-derived suppressor cells in the cervical cancer microenvironment. | 1 |
| 35352250 | 2022 | Polymorphism rs1046495 of the GFER Gene as a New Genetic Marker of Preposition to Type 2 Diabetes Mellitus. | 1 |
| 35352250 | 2022 | Polymorphism rs1046495 of the GFER Gene as a New Genetic Marker of Preposition to Type 2 Diabetes Mellitus. | 1 |
| 33835027 | 2021 | Augmenter of liver regeneration regulates cellular iron homeostasis by modulating mitochondrial transport of ATP-binding cassette B8. | 6 |
| 33835027 | 2021 | Augmenter of liver regeneration regulates cellular iron homeostasis by modulating mitochondrial transport of ATP-binding cassette B8. | 6 |
| 31754973 | 2020 | RASSF1A-Hippo pathway link in patients with urothelial carcinoma of bladder: plausible therapeutic target. | 4 |
| 32031683 | 2020 | Hepatic Deficiency of Augmenter of Liver Regeneration Predisposes to Nonalcoholic Steatohepatitis and Fibrosis. | 15 |
| 31754973 | 2020 | RASSF1A-Hippo pathway link in patients with urothelial carcinoma of bladder: plausible therapeutic target. | 4 |
| 32031683 | 2020 | Hepatic Deficiency of Augmenter of Liver Regeneration Predisposes to Nonalcoholic Steatohepatitis and Fibrosis. | 15 |
| 30500391 | 2019 | Bile acid-induced apoptosis and bile acid synthesis are reduced by over-expression of Augmenter of Liver Regeneration (ALR) in a STAT3-dependent mechanism. | 11 |
| 31155927 | 2019 | Downregulation of WW domain-containing oxidoreductase leads to tamoxifen-resistance by the inactivation of Hippo signaling. | 3 |
| 31166951 | 2019 | TGF-β induces liver fibrosis via miRNA-181a-mediated down regulation of augmenter of liver regeneration in hepatic stellate cells. | 23 |
| 31180521 | 2019 | PLEKHO1 knockdown inhibits RCC cell viability in vitro and in vivo, potentially by the Hippo and MAPK/JNK pathways. | 7 |
| 31822044 | 2019 | Augmenter of Liver Regeneration Alleviates Renal Hypoxia-Reoxygenation Injury by Regulating Mitochondrial Dynamics in Renal Tubular Epithelial Cells. | 9 |
Citation
Dessen P
GFER (growth factor, augmenter of liver regeneration)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46576/gfer
