PPP1R2 (protein phosphatase 1 regulatory inhibitor subunit 2)

2007-04-01  

Identity

HGNC
LOCATION
3q29
LOCUSID
ALIAS
IPP-2,IPP2,PPP1R2A
FUSION GENES

Other Information

Locus ID:

NCBI: 5504
MIM: 601792
HGNC: 9288
Ensembl: ENSG00000184203

Variants:

dbSNP: 5504
ClinVar: 5504
TCGA: ENSG00000184203
COSMIC: PPP1R2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000184203ENST00000413183E7EUI7
ENSG00000184203ENST00000418939H7C416
ENSG00000184203ENST00000438848E7EMN6
ENSG00000184203ENST00000618156P41236
ENSG00000184203ENST00000625807E7EUI7

Expression (GTEx)

0
10
20
30
40
50
60

References

Pubmed IDYearTitleCitations
332388882020The PP1 regulator PPP1R2 coordinately regulates AURKA and PP1 to control centrosome phosphorylation and maintain central spindle architecture.3
332388882020The PP1 regulator PPP1R2 coordinately regulates AURKA and PP1 to control centrosome phosphorylation and maintain central spindle architecture.3
235060012013Identification and characterization of two distinct PPP1R2 isoforms in human spermatozoa.9
241957372013Not so pseudo: the evolutionary history of protein phosphatase 1 regulatory subunit 2 and related pseudogenes.7
235060012013Identification and characterization of two distinct PPP1R2 isoforms in human spermatozoa.9
241957372013Not so pseudo: the evolutionary history of protein phosphatase 1 regulatory subunit 2 and related pseudogenes.7
217144982011Molecular basis for an ancient partnership between prolyl isomerase Pin1 and phosphatase inhibitor-2.7
217144982011Molecular basis for an ancient partnership between prolyl isomerase Pin1 and phosphatase inhibitor-2.7
187160572008Phosphatase inhibitor-2 balances protein phosphatase 1 and aurora B kinase for chromosome segregation and cytokinesis in human retinal epithelial cells.28
190361502008Phosphatase inhibitor 2 promotes acetylation of tubulin in the primary cilium of human retinal epithelial cells.12
187160572008Phosphatase inhibitor-2 balances protein phosphatase 1 and aurora B kinase for chromosome segregation and cytokinesis in human retinal epithelial cells.28
190361502008Phosphatase inhibitor 2 promotes acetylation of tubulin in the primary cilium of human retinal epithelial cells.12
166276252006Inhibition of protein phosphatase 1 by inhibitor-2 gene delivery ameliorates heart failure progression in genetic cardiomyopathy.36
169875142006The protein phosphatase-1/inhibitor-2 complex differentially regulates GSK3 dephosphorylation and increases sarcoplasmic/endoplasmic reticulum calcium ATPase 2 levels.13
166276252006Inhibition of protein phosphatase 1 by inhibitor-2 gene delivery ameliorates heart failure progression in genetic cardiomyopathy.36

Citation

Dessen P

PPP1R2 (protein phosphatase 1 regulatory inhibitor subunit 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46630/ppp1r2