Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10256
MIM: 603272
HGNC: 19700
Ensembl: ENSG00000142675
Variants:
dbSNP: 10256
ClinVar: 10256
TCGA: ENSG00000142675
COSMIC: CNKSR1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34187934 | 2021 | CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP. | 5 |
| 34187934 | 2021 | CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP. | 5 |
| 30450701 | 2018 | CNKSR1 gene defect can cause syndromic autosomal recessive intellectual disability. | 4 |
| 30450701 | 2018 | CNKSR1 gene defect can cause syndromic autosomal recessive intellectual disability. | 4 |
| 27769899 | 2017 | AKT-dependent phosphorylation of the SAM domain induces oligomerization and activation of the scaffold protein CNK1. | 5 |
| 28732488 | 2017 | Expression of the scaffold connector enhancer of kinase suppressor of Ras 1 (CNKSR1) is correlated with clinical outcome in pancreatic cancer. | 8 |
| 27769899 | 2017 | AKT-dependent phosphorylation of the SAM domain induces oligomerization and activation of the scaffold protein CNK1. | 5 |
| 28732488 | 2017 | Expression of the scaffold connector enhancer of kinase suppressor of Ras 1 (CNKSR1) is correlated with clinical outcome in pancreatic cancer. | 8 |
| 27901111 | 2016 | Optogenetic clustering of CNK1 reveals mechanistic insights in RAF and AKT signalling controlling cell fate decisions. | 10 |
| 27901111 | 2016 | Optogenetic clustering of CNK1 reveals mechanistic insights in RAF and AKT signalling controlling cell fate decisions. | 10 |
| 26319181 | 2015 | Differential tyrosine phosphorylation controls the function of CNK1 as a molecular switch in signal transduction. | 4 |
| 26319181 | 2015 | Differential tyrosine phosphorylation controls the function of CNK1 as a molecular switch in signal transduction. | 4 |
| 24825906 | 2014 | EphrinB1 interacts with CNK1 and promotes cell migration through c-Jun N-terminal kinase (JNK) activation. | 15 |
| 24825906 | 2014 | EphrinB1 interacts with CNK1 and promotes cell migration through c-Jun N-terminal kinase (JNK) activation. | 15 |
| 21320536 | 2011 | CNK1 and other scaffolds for Akt/FoxO signaling. | 12 |
Citation
Dessen P
CNKSR1 (connector enhancer of kinase suppressor of Ras 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46650/cnksr1
