QKI (QKI, KH domain containing RNA binding)

2007-04-01  

Identity

HGNC
QKI
LOCATION
6q26
LOCUSID
9444
ALIAS
Hqk,QK,QK1,QK3,hqkI
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9444
MIM: 609590
HGNC: 21100
Ensembl: ENSG00000112531

Variants:

dbSNP: 9444
ClinVar: 9444
TCGA: ENSG00000112531
COSMIC: QKI

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000112531ENST00000275262Q96PU8
ENSG00000112531ENST00000361195Q96PU8
ENSG00000112531ENST00000361752Q96PU8
ENSG00000112531ENST00000361758Q96PU8
ENSG00000112531ENST00000392127Q96PU8
ENSG00000112531ENST00000424802Q96PU8
ENSG00000112531ENST00000453779Q96PU8
ENSG00000112531ENST00000537041F5GXS8
ENSG00000112531ENST00000537124F5H5U6
ENSG00000112531ENST00000537883H0YG47
ENSG00000112531ENST00000544361H0YGD6
ENSG00000112531ENST00000544436F5H8C8
ENSG00000112531ENST00000544823F5GYM3
ENSG00000112531ENST00000545346F5GYT7
ENSG00000112531ENST00000545607H0YFB7

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
DiseaseREACTOMER-HSA-1643685
Diseases of signal transductionREACTOMER-HSA-5663202
Oncogenic MAPK signalingREACTOMER-HSA-6802957
Signaling by BRAF and RAF fusionsREACTOMER-HSA-6802952

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
380723022024Non-adherent culture method affects the proliferation and apoptosis of mesenchymal stem cells through inhibiting LINC00707 to promote RNF6-mediated QKI ubiquitination.0
383720622024Mature microRNA-binding protein QKI promotes microRNA-mediated gene silencing.0
387690282024Involvement of circRNA Regulators MBNL1 and QKI in the Progression of Esophageal Squamous Cell Carcinoma.0
388142172024Circular RNA Circ_0001322 inhibits gastric cancer progression by modulating the miR-1264/QKI axis and suppressing the Hedgehog pathway.0
380723022024Non-adherent culture method affects the proliferation and apoptosis of mesenchymal stem cells through inhibiting LINC00707 to promote RNF6-mediated QKI ubiquitination.0
383720622024Mature microRNA-binding protein QKI promotes microRNA-mediated gene silencing.0
387690282024Involvement of circRNA Regulators MBNL1 and QKI in the Progression of Esophageal Squamous Cell Carcinoma.0
388142172024Circular RNA Circ_0001322 inhibits gastric cancer progression by modulating the miR-1264/QKI axis and suppressing the Hedgehog pathway.0
371460992023RNA Binding Protein Quaking Promotes Hypoxia-induced Smooth Muscle Reprogramming in Pulmonary Hypertension.1
371713862023microRNA-497 slows esophageal cancer development and reverses chemotherapy resistance through its target QKI.0
374287812023The possible molecular mechanism underlying the involvement of the variable shear factor QKI in the epithelial-mesenchymal transformation of oesophageal cancer.0
371460992023RNA Binding Protein Quaking Promotes Hypoxia-induced Smooth Muscle Reprogramming in Pulmonary Hypertension.1
371713862023microRNA-497 slows esophageal cancer development and reverses chemotherapy resistance through its target QKI.0
374287812023The possible molecular mechanism underlying the involvement of the variable shear factor QKI in the epithelial-mesenchymal transformation of oesophageal cancer.0
355442762022Definition of germ layer cell lineage alternative splicing programs reveals a critical role for Quaking in specifying cardiac cell fate.6

Citation

Dessen P

QKI (QKI, KH domain containing RNA binding)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46703/case-report-explorer/teaching-explorer/js/template.js