Identity
HGNC
LOCATION
10q24.1
LOCUSID
ALIAS
HEL-S-35,PGAM-B,PGAMA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5223
MIM: 172250
HGNC: 8888
Ensembl: ENSG00000171314
Variants:
dbSNP: 5223
ClinVar: 5223
TCGA: ENSG00000171314
COSMIC: PGAM1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000171314 | ENST00000334828 | P18669 |
| ENSG00000171314 | ENST00000334828 | Q6FHU2 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36880587 | 2023 | MicroRNA-324-3p inhibits osteosarcoma progression by suppressing PGAM1-mediated aerobic glycolysis. | 5 |
| 37542027 | 2023 | Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1. | 10 |
| 37705495 | 2023 | PGAM1 Inhibition Promotes HCC Ferroptosis and Synergizes with Anti-PD-1 Immunotherapy. | 11 |
| 38093528 | 2023 | RFX6 facilitates aerobic glycolysis-mediated growth and metastasis of hepatocellular carcinoma through targeting PGAM1. | 5 |
| 36880587 | 2023 | MicroRNA-324-3p inhibits osteosarcoma progression by suppressing PGAM1-mediated aerobic glycolysis. | 5 |
| 37542027 | 2023 | Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1. | 10 |
| 37705495 | 2023 | PGAM1 Inhibition Promotes HCC Ferroptosis and Synergizes with Anti-PD-1 Immunotherapy. | 11 |
| 38093528 | 2023 | RFX6 facilitates aerobic glycolysis-mediated growth and metastasis of hepatocellular carcinoma through targeting PGAM1. | 5 |
| 35674458 | 2022 | PGAM1 regulation of ASS1 contributes to the progression of breast cancer through the cAMP/AMPK/CEBPB pathway. | 5 |
| 36224008 | 2022 | PGAM1 Promotes Glycolytic Metabolism and Paclitaxel Resistance via Pyruvic Acid Production in Ovarian Cancer Cells. | 2 |
| 36260520 | 2022 | Matrine induces hepatocellular carcinoma apoptosis and represses EMT and stemness through microRNA-299-3p/PGAM1 axis. | 1 |
| 35674458 | 2022 | PGAM1 regulation of ASS1 contributes to the progression of breast cancer through the cAMP/AMPK/CEBPB pathway. | 5 |
| 36224008 | 2022 | PGAM1 Promotes Glycolytic Metabolism and Paclitaxel Resistance via Pyruvic Acid Production in Ovarian Cancer Cells. | 2 |
| 36260520 | 2022 | Matrine induces hepatocellular carcinoma apoptosis and represses EMT and stemness through microRNA-299-3p/PGAM1 axis. | 1 |
| 32167655 | 2020 | Circ-PGAM1 promotes malignant progression of epithelial ovarian cancer through regulation of the miR-542-3p/CDC5L/PEAK1 pathway. | 24 |
Citation
Dessen P
PGAM1 (phosphoglycerate mutase 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46705/pgam1
