Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 200933
MIM: 609112
HGNC: 29148
Ensembl: ENSG00000174013
Variants:
dbSNP: 200933
ClinVar: 200933
TCGA: ENSG00000174013
COSMIC: FBXO45
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000174013 | ENST00000311630 | P0C2W1 |
| ENSG00000174013 | ENST00000440469 | C9JLC0 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37814093 | 2024 | LncRNA MEG8 ameliorates Parkinson's disease neuro-inflammation through miR-485-3p/FBXO45 axis. | 2 |
| 37814093 | 2024 | LncRNA MEG8 ameliorates Parkinson's disease neuro-inflammation through miR-485-3p/FBXO45 axis. | 2 |
| 35098525 | 2022 | MiR-30a-5p hampers proliferation of lung squamous cell carcinoma through targeting FBXO45. | 2 |
| 35279684 | 2022 | Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation. | 19 |
| 35838331 | 2022 | Fbxo45-mediated NP-STEP(46) degradation via K6-linked ubiquitination sustains ERK activity in lung cancer. | 3 |
| 35098525 | 2022 | MiR-30a-5p hampers proliferation of lung squamous cell carcinoma through targeting FBXO45. | 2 |
| 35279684 | 2022 | Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation. | 19 |
| 35838331 | 2022 | Fbxo45-mediated NP-STEP(46) degradation via K6-linked ubiquitination sustains ERK activity in lung cancer. | 3 |
| 33966034 | 2021 | DNAJB9 suppresses the metastasis of triple-negative breast cancer by promoting FBXO45-mediated degradation of ZEB1. | 20 |
| 34779401 | 2021 | Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation. | 23 |
| 33966034 | 2021 | DNAJB9 suppresses the metastasis of triple-negative breast cancer by promoting FBXO45-mediated degradation of ZEB1. | 20 |
| 34779401 | 2021 | Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation. | 23 |
| 31285543 | 2020 | FBXO45-MYCBP2 regulates mitotic cell fate by targeting FBXW7 for degradation. | 20 |
| 31285543 | 2020 | FBXO45-MYCBP2 regulates mitotic cell fate by targeting FBXW7 for degradation. | 20 |
| 29665250 | 2019 | A genome-wide association study of coping behaviors suggests FBXO45 is associated with emotional expression. | 9 |
Citation
Dessen P
FBXO45 (F-box protein 45)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46728/fbxo45
