Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6048
MIM: 602677
HGNC: 10068
Ensembl: ENSG00000204308
Variants:
dbSNP: 6048
ClinVar: 6048
TCGA: ENSG00000204308
COSMIC: RNF5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000204308 | ENST00000375094 | Q99942 |
| ENSG00000204308 | ENST00000375094 | A0A024RCQ4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38866787 | 2024 | Human gastric cancer progression and stabilization of ATG2B through RNF5 binding facilitated by autophagy-associated CircDHX8. | 0 |
| 38866787 | 2024 | Human gastric cancer progression and stabilization of ATG2B through RNF5 binding facilitated by autophagy-associated CircDHX8. | 0 |
| 36656913 | 2023 | Suppression of KSHV lytic replication and primary effusion lymphoma by selective RNF5 inhibition. | 4 |
| 36737599 | 2023 | The E3 ligase RNF5 restricts SARS-CoV-2 replication by targeting its envelope protein for degradation. | 18 |
| 37816703 | 2023 | Downregulation of EphA2 stability by RNF5 limits its tumor-suppressive function in HER2-negative breast cancers. | 1 |
| 36656913 | 2023 | Suppression of KSHV lytic replication and primary effusion lymphoma by selective RNF5 inhibition. | 4 |
| 36737599 | 2023 | The E3 ligase RNF5 restricts SARS-CoV-2 replication by targeting its envelope protein for degradation. | 18 |
| 37816703 | 2023 | Downregulation of EphA2 stability by RNF5 limits its tumor-suppressive function in HER2-negative breast cancers. | 1 |
| 33469898 | 2021 | RING-finger protein 5 promotes hepatocellular carcinoma progression and predicts poor prognosis. | 5 |
| 34272738 | 2021 | The E3 Ubiquitin Ligase Ring Finger Protein 5 Ameliorates NASH Through Ubiquitin-Mediated Degradation of 3-Hydroxy-3-Methylglutaryl CoA Reductase Degradation Protein 1. | 12 |
| 34518534 | 2021 | The ubiquitin ligase RNF5 determines acute myeloid leukemia growth and susceptibility to histone deacetylase inhibitors. | 23 |
| 33469898 | 2021 | RING-finger protein 5 promotes hepatocellular carcinoma progression and predicts poor prognosis. | 5 |
| 34272738 | 2021 | The E3 Ubiquitin Ligase Ring Finger Protein 5 Ameliorates NASH Through Ubiquitin-Mediated Degradation of 3-Hydroxy-3-Methylglutaryl CoA Reductase Degradation Protein 1. | 12 |
| 34518534 | 2021 | The ubiquitin ligase RNF5 determines acute myeloid leukemia growth and susceptibility to histone deacetylase inhibitors. | 23 |
| 32054686 | 2020 | Ring finger protein 5 activates sterol regulatory element-binding protein 2 (SREBP2) to promote cholesterol biosynthesis via inducing polyubiquitination of SREBP chaperone SCAP. | 13 |
Citation
Dessen P
RNF5 (ring finger protein 5)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46748/rnf5
